Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed.

Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed. Research Abstract Details 

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Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed. Abstract Text:

C S Giess,D M Keating,M P Osborne,J Mester,R Rosenblatt,

OBJECTIVE: The study purpose was to evaluate the rate of development and the rate of change for benign and malignant breast calcifications at the lumpectomy bed. MATERIALS AND METHODS: Retrospective review identified 53 new calcifications at the lumpectomy bed in patients with available mammograms and medical records. Breast Imaging Reporting and Data System (BI-RADS) categories were retrospectively assigned on the basis of initial prospective recommendation for yearly follow-up (category 2), 6-month follow-up (category 3), or biopsy (category 4 or 5). Outcomes were defined as benign for no recurrence at the lumpectomy bed on biopsy or follow-up and malignant if biopsy-proven at the lumpectomy bed. RESULTS: The median rate of development after lumpectomy was 23 months (range, 2-174 months) for benign and 39 months (range, 15-112 months) for malignant calcifications. Fifteen (28%) of 53 calcifications were classified as BI-RADS category 3. Twelve (80%) of 15 were downgraded to BI-RADS category 2 at a median follow-up of 6.5 months (range, 6-16 months); none represented recurrent disease. Three (20%) of 15 were upgraded to BI-RADS category 4 at the 6-month follow-up, one despite stability (benign) and two for increasing pleomorphism (malignant). Nine (17%) of 53 calcifications were classified as BI-RADS category 4 or 5; six (67%) of the nine were malignant and three (33%) were benign at biopsy. Twenty-nine (55%) of 53 calcifications were classified as BI-RADS category 2, none representing recurrent disease. CONCLUSION: Benign calcifications at the lumpectomy bed usually develop earlier than malignant calcifications, but the rate of development overlaps. Most calcifications initially placed in the probably benign category evolve quickly to more benign or more malignant morphology. Most calcifications heralding recurrence appear suspicious on first presentation.

Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed. Publishing Authors By Initials

CS Giess,DM Keating,MP Osborne,J Mester,R Rosenblatt,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

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Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 175

Page Numbers: 789-93

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ISSN: 0361-803X

DAY: 15

MONTH: Sep

YEAR: 2000

Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: pathology

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Grant and Affiliation Information for Comparison of rate of development and rate of change for benign and malignant breast calcifications at the lumpectomy bed.

AFFILIATION: Department of Radiology, The New York Presbyterian Hospital, Strang-Cornell Breast Center, 525 E. 68th St., New York, NY 10021, USA.

Country: UNITED STATES

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MEDLINETA: AJR Am J Roentgenol

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