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Comparison of ocular hypotensive effects of 3 dosages of oral atenolol.

Comparison of ocular hypotensive effects of 3 dosages of oral atenolol. Research Abstract Details 

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  • Comparison of ocular hypotensive effects of 3 dosages of oral atenolol. Abstract Text:

    Oral atenolol (25 mg twice daily and 50 mg and 100 mg once daily) and placebo were tested as additional therapy in a double-masked, randomised, cross-over study. Twenty-four patients (16 with chronic simple glaucoma and 6 with ocular hypertension) participated who had an intraocular pressure (IOP) higher than 21 mmHg. The mean fall of intraocular pressure varied between 28% and 36% and was observed 2 to 6 hours after administration. After 2 weeks of treatment there was still a small fall in intraocular pressure (13%) after 12 hours (for the 25 mg dose) and 24 hours (for the 50 mg and 100 mg dose), but this was not significant (p less than 0.5). There was a fall in blood pressure and reduced pulse rate which persisted for at least 30 hours. Some patients complained of tiredness during treatment periods. Oral atenolol may be useful additional therapy for glaucoma.

    Comparison of ocular hypotensive effects of 3 dosages of oral atenolol. Publishing Authors By Initials

    For similar eye diseases: ocular hypertension research abstracts see: eye diseases: ocular hypertension research

    PUBMED ID PMID:

    MEDLINE DATE:

    Comparison of ocular hypotensive effects of 3 dosages of oral atenolol. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: The British journal of ophthalmology

    VOLUME: 67

    Page Numbers: 664-7

    Journal Abbreviation: Br J Ophthalmol

    ISSN: 0007-1161

    DAY: 28

    MONTH: Oct

    YEAR: 1983

    Comparison of ocular hypotensive effects of 3 dosages of oral atenolol. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 421041

    Comparison of ocular hypotensive effects of 3 dosages of oral atenolol. Keywords Mesh Terms:

    KEYWORDS: Ocular Hypertension

    MESH TERMS: drug therapy

    Chemical & Substance for Abstract: Comparison of ocular hypotensive effects of 3 dosages of oral atenolol. Information

    Substance Name: Atenolol

    Registry Number: 29122-68-7

    Grant and Affiliation Information for Comparison of ocular hypotensive effects of 3 dosages of oral atenolol.

    AFFILIATION:

    Country: ENGLAND

    ENGLAND Research PublicationENGLAND Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Br J Ophthalmol

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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