Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images.

Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images. Research Abstract Details 

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Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images. Abstract Text:

Mark Tseitlin,Amarjot Dhami,Sandra S Eaton,Gareth R Eaton,

Reconstruction of two-dimensional images by filtered back-projection (FBP) and by the maximum entropy method (MEM) was compared for spectral-spatial EPR images with differing signal-to-noise ratios. Experimental projections were recorded using direct-detected rapid scans in the presence of a series of magnetic field gradients. The slow-scan absorption lineshapes were calculated by Fourier deconvolution. A Hamming filter was used in conjunction with FBP, but not for MEM. Imperfections in real experimental data, as well as random noise, contribute to discrepancies between the reconstructed image and experimental projections, which may make it impossible to achieve the customary MEM criterion for convergence. The Cambridge MEM algorithm, with allowance for imperfections in experimental data, produced images with more linear intensity scales and more accurate linewidths for weak signals than was obtained with another MEM method. The more effective elimination of noise in baseline regions by MEM made it possible to detect weak trityl (13)C trityl hyperfine lines that could not be distinguished from noise in images reconstructed by FBP. Another advantage of MEM is that projections do not need to be equally spaced. FBP has the advantages that computational time is less, the amplitude scale is linear, and there is less noise superimposed on peaks in images. It is useful to reconstruct images by both methods and compare results. Our observations indicate that FBP works well when the number of projections is large enough that the star effect is negligible. When there is a smaller number of projections, projections are unequally spaced, and/or signal-to-noise is lower MEM is advantageous.

Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images. Publishing Authors By Initials

M Tseitlin,A Dhami,SS Eaton,GR Eaton,

For similar diagnosis: diagnosis, computer-assisted: image interpretation, computer-assisted research abstracts see: diagnosis: diagnosis, computer-assisted: image interpretation, computer-assisted research

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Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of magnetic resonance (San Diego, Calif. :

VOLUME: 184

Page Numbers: 157-68

Journal Abbreviation: J. Magn. Reson.

ISSN: 1090-7807

DAY: 27

MONTH: 10

YEAR: 2006

Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images. Information

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LANGUAGE: eng

NlmUniqueID: 9707935

Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images. Keywords Mesh Terms:

KEYWORDS: Image Interpretation, Computer-Assisted

MESH TERMS: methods

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Grant and Affiliation Information for Comparison of maximum entropy and filtered back-projection methods to reconstruct rapid-scan EPR images.

AFFILIATION: Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.

Country: United States

AGENCY: United States NIBIB

GRANT: EB002180

ACRONYM: EB

MEDLINETA: J Magn Reson

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