Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates.

Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates. Research Abstract Details 

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Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates. Abstract Text:

Jun-Ichiro Takano,Toyoko Narita,Hiroshi Tachibana,Keiji Terao,Koji Fujimoto,

Three protein-coding loci in DNA of an Entamoeba histolytica strain (EHMfas1) isolated from cynomolgus monkey (Macaca fascicularis) were sequenced; these loci corresponded to the genes for chitinase, the serine-rich E. histolytica protein (SREHP), and the 16 S-like small subunit ribosomal RNA (16S-like SSUrRNA). The nucleotide and deduced amino-acid sequences of chitinase and SREHP were compared with sequences from human isolates. EHMfas1 had several specific mutations in units in the polymorphic regions of the chitinase and SREHP loci, with some repetition of these mutated units. The sequence of the 16S-like SSUrRNA gene (16S-like SSUrDNA) was compared with other Entamoeba species. In phylogenetic analysis, EHMfas1 was not categorized in the E. histolytica cluster but between E. histolytica and E. dispar. To our knowledge, this is the first molecular characterization of E. histolytica isolated from cynomolgus monkey, and our results indicate that EHMfas1 may be a subspecies of E. histolytica that infects cynomolgus monkey.

Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates. Publishing Authors By Initials

J Takano,T Narita,H Tachibana,K Terao,K Fujimoto,

For similar biological phenomena, cell phenomena, and immunity: immunity: antibody specificity: species specificity research abstracts see: biological phenomena, cell phenomena, and immunity: immunity: antibody specificity: species specificity research

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Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Parasitology research

VOLUME: 101

Page Numbers: 539-46

Journal Abbreviation: Parasitol. Res.

ISSN: 0932-0113

DAY: 15

MONTH: 03

YEAR: 2007

Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates. Information

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LANGUAGE: eng

NlmUniqueID: 8703571

Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates. Keywords Mesh Terms:

KEYWORDS: Species Specificity

MESH TERMS: genetics

Chemical & Substance for Abstract: Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates. Information

Substance Name: Chitinase

Registry Number: EC 3.2.1.14

Grant and Affiliation Information for Comparison of Entamoeba histolytica DNA isolated from a cynomolgus monkey with human isolates.

AFFILIATION: The Corporation for Production and Research of Laboratory Primates, 1 Hachimandai, Tsukuba-shi, Ibaraki 305-0843, Japan. takano@primate.or.jp

Country: Germany

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MEDLINETA: Parasitol Res

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