[Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts]

[Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts] Research Abstract Details 

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[Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts] Abstract Text:

K Iwamoto,N Usui,H Kinoshita,

31P magnetic resonance spectroscopy was used to measure high energy phosphates of the heart continuously as an index of the viability of the preserved organ together with the cardiac function after preservation. Results with the simple immersion (SI) and the continuous perfusion (CP) methods were compared. With SI, ATP decreased to 14.8 +/- 4.1% of the base line after 12 hr of preservation, and phosphocreatine decreased to 27.8 +/- 6.2% after 3 hr, remaining at about 30% of the base line thereafter. With CP, ATP and phosphocreatine were unchanged even after 24 hr of preservation; they were 99.1 +/- 2.6% and 119.6 +/- 6.7%, respectively. The ATP/Pi ratio was 5.4 +/- 0.7% after 12 hr with SI and 62.2 +/- 5.8% after 24 hr with CP. LV dP/dt was 96.6 +/- 11.5% after 3 hr of SI (3-SI), which was not significantly different from the control. After 6 hr of SI (6-SI), the value was 122.7 +/- 0.2%, significantly higher (p less than 0.01) than the control. After 9 hr of SI (9-SI) or after 24 hr of CP (24-CP), it was 80.8 +/- 4.6% and 67.8 +/- 8.2%, respectively, both were significantly lower (p less than 0.01) than the control. The rate-pressure product returned to the control level after 3-SI and 6-SI, but after 9-SI or 24-CP, it was 74.2 +/- 3.7% and 53.0 +/- 11.0%, and they were significantly (p less than 0.01) lower than the control.(ABSTRACT TRUNCATED AT 250 WORDS)

[Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts] Publishing Authors By Initials

K Iwamoto,N Usui,H Kinoshita,

For similar biological phenomena, cell phenomena, and immunity: biological phenomena: tissue survival research abstracts see: biological phenomena, cell phenomena, and immunity: biological phenomena: tissue survival research

PUBMED ID PMID:

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[Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: [Zasshi] [Journal]. Nihon Ky?bu Geka Gakkai

VOLUME: 38

Page Numbers: 1262-9

Journal Abbreviation:

ISSN: 0369-4739

DAY: 14

MONTH: Aug

YEAR: 1990

[Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts] Information

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LANGUAGE: jpn

NlmUniqueID: 19130180

[Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts] Keywords Mesh Terms:

KEYWORDS: Tissue Survival

MESH TERMS: methods

Chemical & Substance for Abstract: [Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts] Information

Substance Name: Adenosine Triphosphate

Registry Number: 56-65-5

Grant and Affiliation Information for [Comparison by 31P magnetic resonance spectroscopy of effect of simple immersion and continuous perfusion methods on organ viability of preserved rat hearts]

AFFILIATION: Department of Surgery, Osaka City University Medical School, Japan.

Country: JAPAN

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MEDLINETA: Nippon Kyobu Geka Gakkai Zassh

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