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Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup.

Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. Research Abstract Details 

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  • Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. Abstract Text:

    f kametaniF Kametani,t takayasuT Takayasu,s suzukiS Suzuki,t shinodaT Shinoda,t okuyamaT Okuyama,a shimizuA Shimizu,

    Amino acid sequence analysis was done on a human lambda Bence Jones protein NIG-64 with the major objective of determining the sequence of the variable region. Nineteen tryptic peptides covering 216 residues were isolated from the completely reduced and aminoethylated protein, and 17 of these were completely sequenced. These comprised the entire variable region and 11 from the constant region. For the remaining peptides covering the rest of the constant region, only partial sequences or the amino acid compositions were determined. All the tryptic peptides could be arranged in order on the basis of the above results and homology with other human lambda light chains of the same isotype. The sequence of the variable region of the protein is highly homologous with that of protein New of subgroup V lambda I as compared with other proteins of the same subgroup, suggesting that subgroup V lambda I may be further divided into subsubgroups, namely subsubgroups V lambda I-1 and V lambda I-2.

    Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. Publishing Authors By Initials

    f kametaniF Kametani,t takayasuT Takayasu,s suzukiS Suzuki,t shinodaT Shinoda,t okuyamaT Okuyama,a shimizuA Shimizu,

    For similar enzymes and coenzymes: enzymes: hydrolases: peptide hydrolases: endopeptidases: serine endopeptidases: trypsin research abstracts see: enzymes and coenzymes: enzymes: hydrolases: peptide hydrolases: endopeptidases: serine endopeptidases: trypsin research

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    Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Journal of biochemistry

    VOLUME: 93

    Page Numbers: 421-9

    Journal Abbreviation: J. Biochem.

    ISSN: 0021-924X

    DAY: 19

    MONTH: Feb

    YEAR: 1983

    Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 376600

    Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. Keywords Mesh Terms:

    KEYWORDS: Trypsin

    MESH TERMS: immunology

    Chemical & Substance for Abstract: Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. Information

    Substance Name: Trypsin

    Registry Number: EC 3.4.21.4

    Grant and Affiliation Information for Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup.

    AFFILIATION:

    Country: JAPAN

    JAPAN Research PublicationJAPAN Research Publication

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    MEDLINETA: J Biochem

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