Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates.

Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates. Abstract Text:

Andrew Jackson,Eberhard E Fetz,Andrew Jackson,Eberhard E Fetz,

We describe a small, chronically implantable microwire array for obtaining long-term unit recordings from the cortex of unrestrained nonhuman primates. After implantation, the depth of microwires can be individually adjusted to maintain large-amplitude action potential recordings from single neurons over many months. We present data recorded from the primary motor cortex of two monkeys by autonomous on-board electronic circuitry. Waveforms of individual neurons remained stable for recording periods of several weeks during unrestrained behavior. Signal-to-noise ratios, waveform stability, and rates of cell loss indicate that this method may be particularly suited to experiments investigating the neural correlates of processes extending over multiple days, such as learning and plasticity.

Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates. Publishing Authors By Initials

A Jackson,EE Fetz,A Jackson,EE Fetz,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of neurophysiology

VOLUME: 98

Page Numbers: 3109-18

Journal Abbreviation: J. Neurophysiol.

ISSN: 0022-3077

DAY: 12

MONTH: 09

YEAR: 2007

Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 375404

Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates.

AFFILIATION: Sir James Spence Institute, Royal Victoria Infirmary, Queen Victoria Road, Newcastle-upon-Tyne NE1 4LP, UK. andrew.jackson@ncl.ac.uk).

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Neurophysiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates Related Publications

• Activity-related changes in electrical thresholds of pyramidal tract axons in the behaving monkey.
• Compact movable microwire array for long-term chronic unit recording in cerebral cortex of primates.
• Correlations between the same motor cortex cells and arm muscles during a trained task, free behavior, and natural sleep in the macaque monkey.
• Forelimb movements and muscle responses evoked by microstimulation of cervical spinal cord in sedated monkeys.
• Proceedings: Operant conditioning of EEG for control of human epilepsy.
• Sustained excitatory synaptic input to motor cortex neurons in awake animals revealed by intracellular recording of membrane potentials.
• Volitional control of neural activity: implications for brain-computer interfaces.