We describe a case of a very low birth weight premature female twin with intracardiac thrombosis. Her condition was consistent with neonatal sepsis, and she was treated with advanced life support, antibiotic therapy, parenteral nutrition, blood transfusion, and central venous catheterization. Infective endocarditis was suspected, and a large intracavitary thrombus was detected by two-dimensional Doppler echocardiography. Surgical procedure was not only technically difficult but also highly lethal, being contraindicated in some cases. Consequently, the use of the thrombolytic recombinant tissue-plasminogen activator (rTPA) associated with aspirin was the treatment of choice, and complete dissolution of the thrombus was achieved without adverse effects.
Combined rTPA and aspirin therapy for intracardiac thrombosis in neonates. Publishing Authors By Initials
Combined rTPA and aspirin therapy for intracardiac thrombosis in neonates. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Arquivos brasileiros de cardiologia
VOLUME: 88
Page Numbers: e121-3
Journal Abbreviation: Arq. Bras. Cardiol.
ISSN: 1678-4170
DAY: 25
MONTH: May
YEAR: 2007
Combined rTPA and aspirin therapy for intracardiac thrombosis in neonates. Information
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LANGUAGE: por
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AFFILIATION: Santa Casa de Misericórdia de Vitória, UTI da Criança, Hospital Infantil Nossa Senhora da Glória, Vila Velha, ES, Brazil. ferdialmeida@hotmail.com
Country: Brazil
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MEDLINETA: Arq Bras Cardiol
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