Cognitive predictors of functional decline in vascular dementia.

Cognitive predictors of functional decline in vascular dementia. Research Abstract Details 

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Cognitive predictors of functional decline in vascular dementia. Abstract Text:

Angela L Jefferson,Deborah Cahn-Weiner,Patricia Boyle,Robert H Paul,David J Moser,Norman Gordon,Ronald A Cohen,

BACKGROUND: This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year. METHODS: Twenty-four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant-based measure of instrumental (IADL) and basic activities of daily living (BADL). Follow-up assessment was conducted one-year post-baseline. RESULTS: Logistic regression revealed that changes in the DRS Initiation/Perseveration and DRS Memory subscales were significantly associated with declines in IADLs and BADLs, respectively. CONCLUSIONS: Among patients with VaD, longitudinal changes in IADLs and BADLs are most strongly associated with changes in executive functioning and memory abilities, respectively. Findings suggest that different cognitive functions subserve complex instrumental and rote, habituated basic functional activities, and neuropsychological screening measures are useful in the prediction of such functional changes.

Cognitive predictors of functional decline in vascular dementia. Publishing Authors By Initials

AL Jefferson,D Cahn-Weiner,P Boyle,RH Paul,DJ Moser,N Gordon,RA Cohen,

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Cognitive predictors of functional decline in vascular dementia. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: International journal of geriatric psychiatry

VOLUME: 21

Page Numbers: 752-4

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ISSN: 0885-6230

DAY: 3

MONTH: Aug

YEAR: 2006

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LANGUAGE: eng

NlmUniqueID: 8710629

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AFFILIATION: Alzheimer's Disease Center, Department of Neurology, Boston University Medical Center, Boston, MA 02118, USA. angelaj@bu.edu

Country: England

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MEDLINETA: Int J Geriatr Psychiatry

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