Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer.

Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer. Research Abstract Details 

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Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer. Abstract Text:

Rukhsana Jokhio,Ahmed Farooq Ansari,

OBJECTIVE: To look into the feasibility of using cobra snake venom in suppressing breast cancer tissue through inhibition of nucleic acid synthesis. METHODS: Samples of breast cancerous tissue, obtained from Atomic Energy Medical Center, LMCH, Jamshoro, incubated with varying concentrations of venom and without venom (as controls) were assayed for macromolecular (RNA and DNA) levels RESULTS: No. change in the control samples while a prominent and significant fall in nucleic acid contents has been noted in venom treated tissues. Also, maximum effect was observed with 25ug/ml dose. CONCLUSION: Snake venom strongly inhibited the formation of nucleic acids in the breast cancerous tissues. It may bring a fall in cell proliferation, thus there is hope that venom could be used as an anti-cancerous drug in the future.

Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer. Publishing Authors By Initials

R Jokhio,AF Ansari,

For similar nucleic acids, nucleotides, and nucleosides: nucleic acids research abstracts see: nucleic acids, nucleotides, and nucleosides: nucleic acids research

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Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: JPMA. The Journal of the Pakistan Medical Associat

VOLUME: 55

Page Numbers: 71-3

Journal Abbreviation:

ISSN: 0030-9982

DAY: 12

MONTH: Feb

YEAR: 2005

Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer. Information

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LANGUAGE: eng

NlmUniqueID: 7501162

Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer. Keywords Mesh Terms:

KEYWORDS: Nucleic Acids

MESH TERMS: drug effects

Chemical & Substance for Abstract: Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer. Information

Substance Name: Nucleic Acids

Registry Number: 0

Grant and Affiliation Information for Cobra snake venom reduces significantly tissue nucleic acid levels in human breast cancer.

AFFILIATION: Department of Pliysilogy, University of Sindh, Jamshoro.

Country: Pakistan

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MEDLINETA: J Pak Med Assoc

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