Co-introgression of Y-chromosome haplogroups and the sickle cell gene across Africa's Sahel.

Co-introgression of Y-chromosome haplogroups and the sickle cell gene across Africa's Sahel. Research Abstract Details 

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Co-introgression of Y-chromosome haplogroups and the sickle cell gene across Africa's Sahel. Abstract Text:

Rihab E Bereir,Hisham Y Hassan,Niven A Salih,Peter A Underhill,Luigi L Cavalli-Sforza,Ayman A Hussain,Dominic Kwiatkowski,Muntaser E Ibrahim,Rihab E Bereir,Hisham Y Hassan,Niven A Salih,Peter A Underhill,Luigi L Cavalli-Sforza,Ayman A Hussain,Dominic Kwiatkowski,Muntaser E Ibrahim,Rihab E Bereir,Hisham Y Hassan,Niven A Salih,Peter A Underhill,Luigi L Cavalli-Sforza,Ayman A Hussain,Dominic Kwiatkowski,Muntaser E Ibrahim,

The Sahel that extends from the Atlantic Ocean to the Ethiopian highland is a historical reservoir of Africa's cultures and grandest populations and a known arena of ancient and recent migrations. We are interested in the issue whether such migrations were also carriers of genetic traits and whether this introgression could be associated with population genetic markers. Based on analysis of Y-chromosome haplogroups, we present evidence that the sickle gene, one of the major protective polymorphisms known in malaria, has in fact found its way only recently to the gene pool of the populations in eastern Sahel. We discuss the possible dynamics of the process and give estimates of the age of the introduction of the S allele into eastern Sahel.European Journal of Human Genetics (2007) 15, 1183-1185; doi:10.1038/sj.ejhg.5201892; published online 15 August 2007.

Co-introgression of Y-chromosome haplogroups and the sickle cell gene across Africa's Sahel. Publishing Authors By Initials

RE Bereir,HY Hassan,NA Salih,PA Underhill,LL Cavalli-Sforza,AA Hussain,D Kwiatkowski,ME Ibrahim,RE Bereir,HY Hassan,NA Salih,PA Underhill,LL Cavalli-Sforza,AA Hussain,D Kwiatkowski,ME Ibrahim,RE Bereir,HY Hassan,NA Salih,PA Underhill,LL Cavalli-Sforza,AA Hussain,D Kwiatkowski,ME Ibrahim,

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Co-introgression of Y-chromosome haplogroups and the sickle cell gene across Africa's Sahel. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of human genetics : EJHG

VOLUME: 15

Page Numbers: 1183-5

Journal Abbreviation: Eur. J. Hum. Genet.

ISSN: 1018-4813

DAY: 15

MONTH: 08

YEAR: 2007

Co-introgression of Y-chromosome haplogroups and the sickle cell gene across Africa's Sahel. Information

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LANGUAGE: eng

NlmUniqueID: 9302235

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AFFILIATION: 1Institute of Endemic Diseases, Medical Campus, University of Khartoum, Khartoum, Sudan.

Country: England

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MEDLINETA: Eur J Hum Genet

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