Clozapine use in a forensic population in a New South Wales prison hospital.

Clozapine use in a forensic population in a New South Wales prison hospital. Research Abstract Details 

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Clozapine use in a forensic population in a New South Wales prison hospital. Abstract Text:

Adam Martin, O'Driscoll,Anthony Samuels,Adam Martin, O'Driscoll,Anthony Samuels,

Objective: To document and measure various parameters and outcomes in patients prescribed clozapine in a forensic psychiatric setting. Method: A retrospective file review was conducted on patients prescribed clozapine. Parameters and outcomes were recorded and compared against a group prescribed other antipsychotics, matched for sex and diagnosis. Results: Patients prescribed clozapine had higher rates of substance misuse syndromes and comorbidity when compared to patients prescribed other antipsychotics. Clozapine was found to be effective in treatment of psychosis. High rates of adverse effects were noted. Discontinuation of clozapine for a variety of reasons was common. Conclusion: Patients identified as treatment resistant who are prescribed clozapine are often more complex in the pattern of illness and subsequent needs. Clozapine is effective in the treatment of psychosis in this forensic service. Its benefits need to be balanced against the potential for adverse effects and problems ensuring adherence. Regular, objective monitoring of clinical and adverse effects would aid patient safety, clinical decision-making and future research.

Clozapine use in a forensic population in a New South Wales prison hospital. Publishing Authors By Initials

A Martin,C O'Driscoll,A Samuels,A Martin,C O'Driscoll,A Samuels,

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Clozapine use in a forensic population in a New South Wales prison hospital. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Australian and New Zealand journal of psychiat

VOLUME: 42

Page Numbers: 141-6

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ISSN: 0004-8674

DAY: 16

MONTH: Feb

YEAR: 2008

Clozapine use in a forensic population in a New South Wales prison hospital. Information

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LANGUAGE: eng

NlmUniqueID: 111052

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AFFILIATION: Justice Health, New South Wales, Australia.

Country: England

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MEDLINETA: Aust N Z J Psychiatry

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