Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment.

Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment. Research Abstract Details 

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Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment. Abstract Text:

Clostridium sordellii infections pose difficult clinical challenges and are usually fatal. Most commonly, these infections occur after trauma, childbirth, and routine gynecological procedures, but they have recently been associated with medically induced abortions and injection drug use. We report 2 fatal cases, one of which was associated with minor trauma, and the other of which was associated with normal childbirth, and we summarize the clinical features of 43 additional cases of reported C. sordellii infection. Of these 45 cases, 8 (18%) were associated with normal childbirth, 5 (11%) were associated with medically induced abortion, and 2 (0.4%) were associated with spontaneous abortion. The case-fatality rate was 100% in these groups. Ten (22%) of the C. sordellii infections occurred in injection drug users, and 50% of these patients died. Other cases of C. sordellii infection (in 19 patients [43%]) occurred after trauma or surgery, mostly in healthy persons, and 53% these patients died. Overall, the mortality rate was 69% (31 of 45 patients). Eighty-five percent of all patients with fatal cases died within 2-6 days of initial infection, and nearly 80% of fatal cases developed leukemoid reactions. Rapid diagnostic tests and improved treatments are needed to reduced the morbidity and mortality associated with this devastating infection.

Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment. Publishing Authors By Initials

For similar reproductive and urinary physiology: reproduction: pregnancy research abstracts see: reproductive and urinary physiology: reproduction: pregnancy research

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MEDLINE DATE:

Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Clinical infectious diseases : an official publica

VOLUME: 43

Page Numbers: 1436-46

Journal Abbreviation: Clin. Infect. Dis.

ISSN: 1537-6591

DAY: 30

MONTH: 10

YEAR: 2006

Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment. Information

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LANGUAGE: eng

NlmUniqueID: 9203213

Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment. Keywords Mesh Terms:

KEYWORDS: Pregnancy

MESH TERMS: microbiology

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Grant and Affiliation Information for Clostridium sordellii infection: epidemiology, clinical findings, and current perspectives on diagnosis and treatment.

AFFILIATION: Veterans Affairs Medical Center, Boise, ID 83702, USA. maldape32@hotmail.com

Country: United States

AGENCY: United States NCRR

GRANT: P20RR15587

ACRONYM: RR

MEDLINETA: Clin Infect Dis

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