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[Clinicopathologic features of the patients with node-negative metastasis gastric adenocarcinoma and their survival analysis]

[Clinicopathologic features of the patients with node-negative metastasis gastric adenocarcinoma and their survival analysis] Research Abstract Details 

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  • [Clinicopathologic features of the patients with node-negative metastasis gastric adenocarcinoma and their survival analysis] Abstract Text:

    jian liJian Li,shi-rong caiShi-rong Cai,yu-long heYu-long He,mei-jin huangMei-jin Huang,kai-yong meiKai-yong Mei,jian-ping wangJian-ping Wang,wen-hua zhanWen-hua Zhan,

    OBJECTIVE: To investigate the clinicopathologic features of the patients with node-negative metastasis (pN0) gastric carcinoma confirmed by routine pathologic examination (Ha&E staining),and their relationship with survival. METHODS: The clinico-pathologic data of 87 pN0 gastric carcinoma patients were analyzed retrospectively. Kaplan-Meier (Log-rank) method was used to compare the survival rate,and Cox regression method was used to screen the independent prognosis factors for pN0 gastric cancer. RESULTS: There were 69 males and 18 females. D(2) lymphadenectomy was performed in 75 (86.2%), and D(3) in 13 cases (13.8%). Distal gastrectomy was performed in 59 (67.8%), total gestrectomy in 24 (27.6%) and proximal gastrectomy in l4 cases (4.6%). Twenty-three (26.4%) cases received postoperative chemotherapy and 64 (73.6% ) did not. The 5-year survival rate of the 87 pN0 gastric carcinoma patients was 56.5%. There were no differences in survival rate considering age, tumor location, gastrectomy, lymph nodes dissection, differentiation grade, and tumor-stroma relationship (P > 0.05), while the differences were significant in survival rate between the patients with postoperative chemotherapy,lymphatic invasion,venous invasion or not,and different pT staging (all Pa< 0.05). The Cox regression analysis revealed that pT staging and postoperative chemotherapy were independent prognostic factors. CONCLUSION: pT staging and postoperative chemotherapy are independent prognostic factors. It is necessary to develop a precise staging technique to select a suitable surgical therapy or confirm which patients should accept postoperative chemotherapy in pN0 gastric carcinoma patients.

    [Clinicopathologic features of the patients with node-negative metastasis gastric adenocarcinoma and their survival analysis] Publishing Authors By Initials

    j liJ Li,sr caiSR Cai,yl heYL He,mj huangMJ Huang,ky meiKY Mei,jp wangJP Wang,wh zhanWH Zhan,

    For similar abstracts research abstracts see: abstracts research

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    [Clinicopathologic features of the patients with node-negative metastasis gastric adenocarcinoma and their survival analysis] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Zhonghua wei chang wai ke za zhi = Chinese journal

    VOLUME: 9

    Page Numbers: 230-3

    Journal Abbreviation:

    ISSN: 1671-0274

    DAY: 24

    MONTH: May

    YEAR: 2006

    [Clinicopathologic features of the patients with node-negative metastasis gastric adenocarcinoma and their survival analysis] Information

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    LANGUAGE: chi

    NlmUniqueID: 101177990

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    Grant and Affiliation Information for [Clinicopathologic features of the patients with node-negative metastasis gastric adenocarcinoma and their survival analysis]

    AFFILIATION: Department of Gastrointestinopancreatic Surgery, The First Affiliated Hospital, Sun Yet-sen University, Guangzhou 510080, China.

    Country: China

    China Research PublicationChina Research Publication

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    MEDLINETA: Zhonghua Wei Chang Wai Ke Za Z

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