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[Clinical study on the postburn change in the hypothalamus-pituitary-adrenal hormones in severely burned patients]

[Clinical study on the postburn change in the hypothalamus-pituitary-adrenal hormones in severely burned patients] Research Abstract Details 

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  • [Clinical study on the postburn change in the hypothalamus-pituitary-adrenal hormones in severely burned patients] Abstract Text:

    hong-mian liHong-mian Li,zi-qian liangZi-qian Liang,zuo-jie luoZuo-jie Luo,

    OBJECTIVE: To investigate the postburn dynamic changes in the hypothalamus-pituitary-adrenal hormones in severely burned patients. METHODS: Fifty burn patients were enrolled in the study. The plasma contents of total GC (cortisol), ACTH and aldosterone (ALDO) and urinary contents of 17-OHO and 17-KS were determined with radio-immunological assay (RIA) method after burn injury to compare with the normal values which were well established clinically. RESULTS: The postburn plasma and urinary contents of the above indices were increased evidently with two peak values in shock and infectious stages, whilst the majority of he indices were lower than the normal values after 6 postburn weeks (PBWs). The values of these hormones were the lowest in dying patients. On the other hand, the values approached normal levels in those patients whose burn wounds were healing. CONCLUSION: Increases of the plasma and urinary levels of hypothalamus-pituitary -adrenal hormones in severely burned patients were constantly seen. Burn shock and infection seemed to be the two major factors in inducing postburn stress reaction in burn victims. Abrupt decrease of the hormone levels in plasma and or urine indicated adrenal failure predicting a poor prognosis of the burn patients.

    [Clinical study on the postburn change in the hypothalamus-pituitary-adrenal hormones in severely burned patients] Publishing Authors By Initials

    hm liHM Li,zq liangZQ Liang,zj luoZJ Luo,

    For similar abstracts research abstracts see: abstracts research

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    [Clinical study on the postburn change in the hypothalamus-pituitary-adrenal hormones in severely burned patients] Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang za

    VOLUME: 19

    Page Numbers: 169-71

    Journal Abbreviation:

    ISSN: 1009-2587

    DAY: 18

    MONTH: Jun

    YEAR: 2003

    [Clinical study on the postburn change in the hypothalamus-pituitary-adrenal hormones in severely burned patients] Information

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    LANGUAGE: chi

    NlmUniqueID: 100959418

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    Grant and Affiliation Information for [Clinical study on the postburn change in the hypothalamus-pituitary-adrenal hormones in severely burned patients]

    AFFILIATION: The Center of Burn, Plastic Surgery and Rehabilitation, The first Affiliated Hospital of Guang Xi Medical University, Nanning 530021, PR China.

    Country: China

    China Research PublicationChina Research Publication

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    MEDLINETA: Zhonghua Shao Shang Za Zhi

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