[Clinical study on preventive effect of fuzheng quxie granule on respiratory viral infection]

[Clinical study on preventive effect of fuzheng quxie granule on respiratory viral infection] Research Abstract Details 

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[Clinical study on preventive effect of fuzheng quxie granule on respiratory viral infection] Abstract Text:

Jing-Cheng Dong,Zhao-Hua Gong,Yu-Hua Liu,Jinyu Xie,Xiaohui Dong,Fudong Zhao,Yan Cui,Jing-Cheng Dong,Zhao-Hua Gong,Yu-Hua Liu,Jinyu Xie,Xiaohui Dong,Fudong Zhao,Yan Cui,

OBJECTIVE: To evaluate the effect of Fuzheng Quxie granule (FQG) on immune cells and cytokines of populations susceptible to respiratory viral infection. METHODS: One thousand four hundred and two subjects selected from 25 hospitals in Shanghai between May and June in 2003, were divided into the FQG group treated with FQG and the control group treated with placebo. Serum levels of interleukin 2 (IL-2), interleukin 4 (IL-4), gamma-interferon (gamma-IFN), blood lymphocyte subsets (CD3+ , CD4+, CD8+), B-cell count and natural killer cell (NK) percent ratio were measured in 130 of the FQG group and 120 of the control group before treatment, by the end of the 2nd week and two weeks after treatment. RESULTS: By the end of the 2nd week of treatment, as compared with before treatment, the levels of IL-2, gamma-IFN, and NK percent in the FQG group increased significantly (P < 0.05), while IL-4 and CD3+, CD4+, CD8+ and B-cell count were unchanged. Besides, levels of Th1/Th2 ratio markedly increased at the end of the 2nd week and two weeks after treatment, in comparing with that before treatment and in the control group (P<0.05). CONCLUSION: FQG could improve immune function of population susceptible to respiratory viral infection certain extent.

[Clinical study on preventive effect of fuzheng quxie granule on respiratory viral infection] Publishing Authors By Initials

JC Dong,ZH Gong,YH Liu,J Xie,X Dong,F Zhao,Y Cui,JC Dong,ZH Gong,YH Liu,J Xie,X Dong,F Zhao,Y Cui,

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[Clinical study on preventive effect of fuzheng quxie granule on respiratory viral infection] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongx

VOLUME: 26

Page Numbers: 215-7

Journal Abbreviation: Zhongguo Zhong Xi Yi Jie He Za

ISSN: 1003-5370

DAY: 14

MONTH: Mar

YEAR: 2006

[Clinical study on preventive effect of fuzheng quxie granule on respiratory viral infection] Information

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LANGUAGE: chi

NlmUniqueID: 9211576

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AFFILIATION: Institute of Integrated Traditional Chinese and Western Medicine on Pulmonary and Atopic Diseases, Huashan Hospital Affiliated to Fudan University, Shanghai (200040). jcdong2004@hotmail.com

Country: China

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MEDLINETA: Zhongguo Zhong Xi Yi Jie He Za

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