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[Clinical study of P-gp, and bcl-2 protein expression in non-Hodgkin's lymphomas patients]

[Clinical study of P-gp, and bcl-2 protein expression in non-Hodgkin's lymphomas patients] Research Abstract Details 

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  • [Clinical study of P-gp, and bcl-2 protein expression in non-Hodgkin's lymphomas patients] Abstract Text:

    x fuX Fu,d yuD Yu,y maoY Mao,x yangX Yang,j heJ He,y keY Ke,l yangL Yang,h jiangH Jiang,c wuC Wu,h dengH Deng,

    OBJECTIVE: To investigate the relationship between the expression of P-gp, P26-bcl-2 and the prognosis in intermediate and high grade non-Hodgkin's lymphomas (NHL). METHODS: Sixty cases of intermediate and high grade NHL were retrospectively reviewed using immunohistochemical method. All patients were received CHOP chemotherapy over 4 courses. RESULTS: P-gp was identified in 15 and P26-bcl-2 in 25 cases. The 3-year survival rates for patients with P26-bcl-2 (+) and P26-bcl-2 (-) were 37.64% and 76.80%, respectively (P < 0.005), and for patients with both positive P-gp and P26-bcl-2 and both negative were 15.38% and 48.48%, respectively (P = 0.038). CONCLUSIONS: There is direct relationship between the P-gp, P26-bcl-2 protein expression and the prognosis in intermediate and high grade non-Hodgkin's lymphoma.

    [Clinical study of P-gp, and bcl-2 protein expression in non-Hodgkin's lymphomas patients] Publishing Authors By Initials

    x fuX Fu,d yuD Yu,y maoY Mao,x yangX Yang,j heJ He,y keY Ke,l yangL Yang,h jiangH Jiang,c wuC Wu,h dengH Deng,

    For similar abstracts research abstracts see: abstracts research

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    [Clinical study of P-gp, and bcl-2 protein expression in non-Hodgkin's lymphomas patients] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zaz

    VOLUME: 22

    Page Numbers: 310-2

    Journal Abbreviation: Zhonghua Xue Ye Xue Za Zhi

    ISSN: 0253-2727

    DAY: 5

    MONTH: Jun

    YEAR: 2001

    [Clinical study of P-gp, and bcl-2 protein expression in non-Hodgkin's lymphomas patients] Information

    Number of References:

    LANGUAGE: chi

    NlmUniqueID: 8212398

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    Grant and Affiliation Information for [Clinical study of P-gp, and bcl-2 protein expression in non-Hodgkin's lymphomas patients]

    AFFILIATION: Hubei Cancer Hospital, Wuhan 430079, China.

    Country: China

    China Research PublicationChina Research Publication

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    MEDLINETA: Zhonghua Xue Ye Xue Za Zhi

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