Clinical management of autoimmune pancreatitis.

Clinical management of autoimmune pancreatitis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Clinical management of autoimmune pancreatitis. Abstract Text:

T Kamisawa,K Satake,

Autoimmune pancreatitis (AIP) is a newly described entity with characteristic clinical, radiological, serological, and histological features, in which autoimmune mechanisms seem to be involved in pathogenesis. Many new clinical aspects of AIP have been clarified during 10 years, and AIP has become a distinct entity recognized worldwide. However, precise pathogenesis or pathophysiology remains unclear. As AIP responds dramatically to steroid therapy, accurate diagnosis of AIP is necessary to avoid unnecessary laparotomy or pancreatic resection. It is importance to misdiagnose pancreatic cancer as AIP as well as to misdiagnose AIP as pancreatic cancer. In the absence of a diagnostic serological marker for AIP, its diagnosis rests on identifying unique patterns of abnormalities. Japanese criteria are based on the minimum consensus features of AIP and aim to avoid misdiagnosis of malignancy. It contain 3 items: (1) enlargement of the pancreas and narrowing of the main pancreatic duct; (2) high serum gammaglobulin, IgG, or IgG4, or the presence of autoantibodies; (3) histological findings of lymphoplasmacytic infiltration and fibrosis in the pancreas. For diagnosing AIP, the presence of the imaging criterion is essential. Other clinical characteristics of AIP are elderly male preponderance, fluctuating obstructive jaundice without pain, occasional association with diabetes mellitus and extrapancreatic lesions, and favorite responsiveness to oral steroid therapy. Elevation of serum IgG4 levels and infiltration of abundant IgG4-positive plasma cells in various organs are rather specific in AIP patients. In an elderly male presenting obstructive jaundice and pancreatic mass, AIP should be considered as one of differential diagnoses.

Clinical management of autoimmune pancreatitis. Publishing Authors By Initials

T Kamisawa,K Satake,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Clinical management of autoimmune pancreatitis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Advances in medical sciences

VOLUME: 52

Page Numbers: 61-5

Journal Abbreviation:

ISSN: 1896-1126

DAY: 25

MONTH: 01

YEAR: 2007

Clinical management of autoimmune pancreatitis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101276222

Clinical management of autoimmune pancreatitis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Clinical management of autoimmune pancreatitis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Clinical management of autoimmune pancreatitis.

AFFILIATION: Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113-8677, Japan. kamisawa@cick.jp

Country: Poland

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Adv Med Sci

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Clinical management of autoimmune pancreatitis Related Publications

• 4-O-Acetyl mycarose. A new O-acetyl sugar obtained from leucomycin minor components.
• A SMAP Gene Family Encoding ARF GTPase-Activating Proteins and Its Implication in Membrane Trafficking.
• A novel sphingophosphonoglycolipid containing 3-O-methylgalactose isolated from the skin of the marine gastropod Aplysia kurodai.
• ACID AND ALKALINE DEGRADATION OF THE TNP-AMINO ACIDS AND -PEPTIDES.
• An enzyme cycling method for measurement of allantoin in human serum.
• Biochemical characterization of the neuron. ATPase and acetylcholinesterase activities of neuronal cell bodies isolated in bulk from the pig brain stem.
• Characterization of phosphonoglycosphingolipids containing pyruvate: localization in Aplysia nerve bundles.
• Chemical Constituents of Morinda citrifolia Roots Exhibit Hypoglycemic Effects in Streptozotocin-Induced Diabetic Mice.
• Clathrin dependent endocytosis of E-cadherin is regulated by the Arf6GAP isoform SMAP1.
• Clinical management of autoimmune pancreatitis.
• Comparison of 30 immunity-related genes from the common marmoset with orthologues from human and mouse.
• Different stability of N- and C-domain of diferric ovotransferrin in urea and application to the determination of iron distribution between the two domains.
• Fluorescence Response of a 4-Trifluoroacetylaminophthalimide to Iodide Ions upon 254 nm Irradiation in MeCN.
• Functions of a GnRH receptor heterodimer of the ascidian, Ciona intestinalis. Short communication.
• Gangliosides in neuron.
• Glycolipids in the nervous tissue of invertebrate.
• HEMOGLOBINS FROM ERYTHROCYTES OF EEL, ANGUILLA JAPONICA.
• Heterogeneity of hemoglobin from Arca (Anadara satowi). Molecular weights and oxygen equilibria of Arca Hb I and II.
• Immunochemical and histochemical studies on a phosphonoglycosphingolipid, SGL-II, isolated from the sea gastropod Aplysia kurodai.
• Isolation and characterization of a novel 2-aminoethylphosphonyl-glycosphingolipid from the sea hare, Aplysia kurodai.
• Negative cooperativity of chicken ovotransferrin on Al(III)-binding.
• On the chemical structure of porcine globin alpha.
• On the molecular weight of hemoglobin from Anadara inflata at various pH.
• Selective modification of myosin SH1 with 1,2,4-trinitrobenzene. VIII. Thiols of myosin.
• Steady state characteristics of acclimated hydrogenotrophic methanogens on inorganic substrate in continuous chemostat reactors.
• Structural analysis of a novel triphosphonoglycosphingolipid from the egg of the sea hare, Aplysia kurodai.
• Studies on insulin. IV. On the amino acid composition of the glycyl chain of Bonito insulin-I.
• The spectrophotometric determination as trinitrophenyl derivatives of amino acids and peptides resolved on paper by electrophoresis and chromatography.
• [Calcium oxalate crystals in several kinds of Cinnamon bark]
• [Patterns of mediastinal and supraclavicular metastases in apical invasive lung cancer--importance of supraclavicular lymph node dissection]