Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer.

Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer. Abstract Text:

Makito Okamoto,Hiroomi Takahashi,Kazuo Yao,Katsuhide Inagi,Meijin Nakayama,Hiromi Nagai,

Eighty-eight patients with hypopharyngeal cancer who received chemoradiotherapy as the primary treatment between 1979 and 1997 were investigated. Forty-six patients who received surgery as the primary treatment were analyzed as a control group. There were no statistically significant differences regarding TN classification, tumor stage, tumor site, age or sex between the radiation and surgery groups. The 5-year cumulative survival rate of primary chemoradiotherapy was 47% and this did not differ significantly from that for the primary surgery group. The larynx was preserved in 74% of cases in the primary chemoradiotherapy group, a far better preservation rate than that in the surgery group. After primary chemoradiotherapy, complete remission (CR) was observed in 59% of cases and the average period of CR was 38 months. Among patients with residual tumor, a salvage operation was employed in 31 cases, 13 patients refused to receive surgery and 8 were inoperable. A salvage operation was performed in 35% of all cases and the 5-year cumulative survival rate was 50%. Based on the 5-year survival, primary CR, salvage and laryngeal preservation rates, we conclude that chemoradiotherapy is a good primary treatment for hypopharyngeal cancer.

Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer. Publishing Authors By Initials

M Okamoto,H Takahashi,K Yao,K Inagi,M Nakayama,H Nagai,

For similar heterocyclic compounds: heterocyclic compounds, 1-ring: pyrimidines: pyrimidinones: uracil research abstracts see: heterocyclic compounds: heterocyclic compounds, 1-ring: pyrimidines: pyrimidinones: uracil research

PUBMED ID PMID:

MEDLINE DATE:

Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta oto-laryngologica. Supplementum

VOLUME:

Page Numbers: 11-4

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 2002

Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370355

Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer. Keywords Mesh Terms:

KEYWORDS: Uracil

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer. Information

Substance Name: Uracil

Registry Number: 66-22-8

Grant and Affiliation Information for Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer.

AFFILIATION: Department of Otorhinolaryngology, School of Medicine, Kitasato University, Kanagawa, Japan. okamotom@med.kitasato-u.ac.jp

Country: Norway

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Acta Otolaryngol Suppl

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Clinical impact of using chemoradiotherapy as a primary treatment for hypopharyngeal cancer Related Publications

• A pigmented calcifying cystic odontogenic tumor associated with compound odontoma: a case report and review of literature.
• Amiodarone and N-desethylamiodarone enhance endothelial nitric oxide production in human endothelial cells.
• Annual abdominal ultrasonographic examination after curative NSCLC resection.
• Capacity analysis for a two-level decoupled Hamming network for associative memory under a noisy environment.
• Characterization of PsTX-60B, a new membrane-attack complex/perforin (MACPF) family toxin, from the venomous sea anemone Phyllodiscus semoni.
• Cloning and characterization of rat casein kinase 1epsilon.
• Development of bovine in vitro-matured follicular oocytes activated with ethanol.
• Effects of central injection of l-carnosine on sympathetic nerve activity innervating brown adipose tissue and body temperature in rats.
• Full-term development of in vitro-matured, vitrified and fertilized bovine oocytes.
• High-throughput solid-phase extraction of metal ions using an iminodiacetate chelating porous disk prepared by graft polymerization.
• Identification of deamidation and isomerization sites on pharmaceutical recombinant antibody using H(2)(18)O.
• Immobilized rhBMP-2/succinylated type I atelocollagen gene expression of intracellular signaling molecules on ST2 cells.
• Immunolocalization of cell signaling molecules in the granular cell ameloblastoma.
• Inhibitory effect of palatinose on glucose absorption in everted rat gut.
• Isolation and characterization of a novel protein toxin from fire coral.
• Lactobacillus Acidophilus strain L-92 regulates the production of Th1 cytokine as well as Th2 cytokines.
• Mastoid obliteration by BMP-2/collagen composites: an experimental study using tissue engineering.
• Minimum leakage rate (0.5%) of stapled esophagojejunostomy with sacrifice of a small part of the jejunum after total gastrectomy in 390 consecutive patients.
• Morbidity prevalence rate of kawasaki disease assessed by single cross-sectional history-taking.
• Natural course of lower urinary tract symptoms following discontinuation of alpha-1-adrenergic blockers in patients with benign prostatic hyperplasia.
• Nutritional status and risk of amyotrophic lateral sclerosis in Japan.
• Preparation and characterization of platinum-ruthenium bimetallic nanoparticles using reverse microemulsions for fuel cell catalyst.
• Production of platelet-activating factor during focal cerebral ischemia and reperfusion in the rat.
• Salvage esophagectomy following definitive chemoradiotherapy.
• Solid tumor resection by use of a highly sensitive micromagnetic needle detection system.
• Subjective effect of magnetic resonance-guided focused ultrasound surgery for uterine fibroids.
• Thrombomodulin is a clock-controlled gene in vascular endothelial cells.
• [A case of loxoprofen sodium-induced eosinophilic pneumonia that occurred ipsilaterally after VATS lobectomy for lung cancer]
• [Cardiac gene therapy]
• [Trends in molecular targeting therapeutics for chronic myeloid leukemia]