Clinical features, topographic patterns on DWI and etiology of thalamic infarcts.

Clinical features, topographic patterns on DWI and etiology of thalamic infarcts. Research Abstract Details 

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Clinical features, topographic patterns on DWI and etiology of thalamic infarcts. Abstract Text:

Xin Wang, Yu Hua Fan,Wynnie W M Lam,Thomas W H Leung, Ka Sing Wong,Xin Wang,Yu Hua Fan,Wynnie W M Lam,Thomas W H Leung,Ka Sing Wong,

Thalamic infarcts may lead to diverse neurological disturbances, which easily results in misdiagnosis. Diffusion-weighed magnetic resonance imaging (DWI) is sensitive for the early diagnosis of the infarct and identification of the territory involved. The aim of this study was to analyze the clinical features, topographic appearance on DWI and etiology of thalamic infarcts. We reviewed clinical data, vascular risk factors, topographic patterns and etiology of thalamic infarcts. The patients were divided into 2 groups according to DWI patterns: isolated thalamic infarcts (ISO-TH) and combined thalamic infarcts (COM-TH). The former were further subdivided into 2 subgroups: inferolateral isolated thalamic infarcts (INF-TH) and non-inferolateral isolated thalamic infarcts (NON-INF) according to the vascular territories. The Patients were also divided according to etiology based on TOAST classification. The association of clinical features, DWI patterns and etiology was analyzed. Twenty nine patients were included, among which, 23 (79.3%) were ISO-TH and 6 (20.7%) were COM-TH. The most common territory involved in the ISO-TH was inferolateral territory [n=17 (73.9%)], followed by tuberothalamic artery territory [n=3 (13.0%)], and posterior choroidal artery territory [n=2 (8.7%)]. In COM-TH, the most common territory also was the inferolateral territory (n=3), followed by posterior choroidal artery territory (n=1). In 2 patients, the lesions involved more than one vascular thalamic territory. Significant association between small-vessel occlusion (SVO) and ISO-TH (INF-TH+NON-IFN) infarcts were found. Our study suggested that SVO was more prevalent in ISO-TH, and COM-TH needed more etiological examination. DWI might provide meaningful clues about etiology of thalamic infarcts.

Clinical features, topographic patterns on DWI and etiology of thalamic infarcts. Publishing Authors By Initials

X Wang, Yu Hua Fan,WW Lam,TW Leung, Ka Sing Wong,X Wang,YH Fan,WW Lam,TW Leung,KS Wong,

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Clinical features, topographic patterns on DWI and etiology of thalamic infarcts. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of the neurological sciences

VOLUME: 267

Page Numbers: 147-53

Journal Abbreviation: J. Neurol. Sci.

ISSN: 0022-510X

DAY: 15

MONTH: Apr

YEAR: 2008

Clinical features, topographic patterns on DWI and etiology of thalamic infarcts. Information

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LANGUAGE: eng

NlmUniqueID: 375403

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AFFILIATION: Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, China; Department of Neurology, the Qingdao Municipal Hospital, Qingdao, China.

Country: Netherlands

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MEDLINETA: J Neurol Sci

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