Clinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderly.

Clinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderly. Research Abstract Details 

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Clinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderly. Abstract Text:

Autoimmune hepatitis affects all ages, and it is probably under-diagnosed in the elderly. Patients aged >/=60 years have a higher frequency of cirrhosis at presentation than adults aged 18 months) and repeated therapies after relapse. Adjustments in the management strategy are warranted for an incomplete response or a need for re-treatment after relapse. Azathioprine (2 mg/kg/day) should be used as a corticosteroid-sparing, long-term maintenance therapy in these instances. Treatment failure is uncommon in the elderly, and age-related changes in the cellular immune response may attenuate the disease and enhance its response to therapy. Concurrent adjuvant therapies must focus on maintenance of bone density.

Clinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderly. Publishing Authors By Initials

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Clinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderly. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Drugs & aging

VOLUME: 25

Page Numbers: 219-39

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ISSN: 1170-229X

DAY: 11

MONTH: 03

YEAR: 2008

Clinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderly. Information

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LANGUAGE: eng

NlmUniqueID: 9102074

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Grant and Affiliation Information for Clinical features, differential diagnosis and treatment of autoimmune hepatitis in the elderly.

AFFILIATION: Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

Country: New Zealand

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MEDLINETA: Drugs Aging

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