Clinical diagnostic criteria for dementia associated with Parkinson's disease.

Clinical diagnostic criteria for dementia associated with Parkinson's disease. Research Abstract Details 

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Clinical diagnostic criteria for dementia associated with Parkinson's disease. Abstract Text:

Murat Emre,Dag Aarsland,Richard Brown,David J Burn,Charles Duyckaerts,Yoshikino Mizuno,Gerald Anthony Broe,Jeffrey Cummings,Dennis W Dickson,Serge Gauthier,Jennifer Goldman,Christopher Goetz,Amos Korczyn,Andrew Lees,Richard Levy,Irene Litvan,Ian McKeith,Warren Olanow,Werner Poewe,Niall Quinn,Christina Sampaio,Eduardo Tolosa,Bruno Dubois,Murat Emre,Dag Aarsland,Richard Brown,David J Burn,Charles Duyckaerts,Yoshikino Mizuno,Gerald Anthony Broe,Jeffrey Cummings,Dennis W Dickson,Serge Gauthier,Jennifer Goldman,Christopher Goetz,Amos Korczyn,Andrew Lees,Richard Levy,Irene Litvan,Ian McKeith,Warren Olanow,Werner Poewe,Niall Quinn,Christina Sampaio,Eduardo Tolosa,Bruno Dubois,

Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD-D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD-D. The Task Force members were assigned to sub-committees and performed a systematic review of the literature, based on pre-defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD-D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point-prevelance is close to 30%, older age and akinetic-rigid form are associated with higher risk. PD-D is characterized by impairment in attention, memory, executive and visuo-spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body-type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD-D are proposed.

Clinical diagnostic criteria for dementia associated with Parkinson's disease. Publishing Authors By Initials

M Emre,D Aarsland,R Brown,DJ Burn,C Duyckaerts,Y Mizuno,GA Broe,J Cummings,DW Dickson,S Gauthier,J Goldman,C Goetz,A Korczyn,A Lees,R Levy,I Litvan,I McKeith,W Olanow,W Poewe,N Quinn,C Sampaio,E Tolosa,B Dubois,M Emre,D Aarsland,R Brown,DJ Burn,C Duyckaerts,Y Mizuno,GA Broe,J Cummings,DW Dickson,S Gauthier,J Goldman,C Goetz,A Korczyn,A Lees,R Levy,I Litvan,I McKeith,W Olanow,W Poewe,N Quinn,C Sampaio,E Tolosa,B Dubois,

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Clinical diagnostic criteria for dementia associated with Parkinson's disease. Journal Published:

PUBLICATION TYPE: Review

Journal: Movement disorders : official journal of the Movem

VOLUME: 22

Page Numbers: 1689-707; quiz 1837

Journal Abbreviation: Mov. Disord.

ISSN: 0885-3185

DAY: 15

MONTH: Sep

YEAR: 2007

Clinical diagnostic criteria for dementia associated with Parkinson's disease. Information

Number of References: 179

LANGUAGE: eng

NlmUniqueID: 8610688

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AFFILIATION: Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. muratemre@superonline.com

Country: United States

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MEDLINETA: Mov Disord

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