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Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study).

Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study). Research Abstract Details 

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  • Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study). Abstract Text:

    shunichi satoShunichi Sato,akiharu watanabeAkiharu Watanabe,yasutoshi mutoYasutoshi Muto,kazuyuki suzukiKazuyuki Suzuki,akinobu katoAkinobu Kato,hisataka moriwakiHisataka Moriwaki,masahiko katoMasahiko Kato,teiji nakamuraTeiji Nakamura, ,

    This multicenter study compared the effects of branched-chain amino acid granules (Livact((R)) Granules, LIV) and an enteral nutrient for chronic hepatic failure (Aminoleban((R)) EN, EN) on serum albumin in patients with decompensated liver cirrhosis. This study enrolled "patients with decompensated liver cirrhosis associated with hepatic encephalopathy who were suffering from hypoalbuminemia in spite of adequate food intake," a condition for which both drugs are indicated. Enrolled patients were randomized to the two groups according to the central registration method. This study continued for 24 weeks. Selected foods were supplied to each patient in principle so that caloric and protein intakes were standardized between the two groups. A total of 281 patients were enrolled. LIV was not inferior to EN concerning the primary efficacy endpoint changes in serum albumin.

    Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study). Publishing Authors By Initials

    s satoS Sato,a watanabeA Watanabe,y mutoY Muto,k suzukiK Suzuki,a katoA Kato,h moriwakiH Moriwaki,m katoM Kato,t nakamuraT Nakamura, ,

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    Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study). Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Hepatology research : the official journal of the

    VOLUME: 31

    Page Numbers: 232-40

    Journal Abbreviation:

    ISSN: 1386-6346

    DAY: 23

    MONTH: 03

    YEAR: 2005

    Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study). Information

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    LANGUAGE: eng

    NlmUniqueID: 9711801

    Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study). Keywords Mesh Terms:

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    Chemical & Substance for Abstract: Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study). Information

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    Grant and Affiliation Information for Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study).

    AFFILIATION: Iwate Medical University, 19-1 Uchimaru, Morioka 020-8505, Japan.

    Country: Netherlands

    Netherlands Research PublicationNetherlands Research Publication

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    MEDLINETA: Hepatol Res

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    Clinical comparison of branched-chain amino acid l-Leucine, l-Isoleucine, l-Valine granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis LIV-EN study Related Publications

     

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