Clinical characteristics and outcome of Candida keratitis.

Clinical characteristics and outcome of Candida keratitis. Research Abstract Details 

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Clinical characteristics and outcome of Candida keratitis. Abstract Text:

Regina L Sun,Dan B Jones,Kirk R Wilhelmus,

PURPOSE: To characterize the clinical features and therapeutic outcome of Candida keratitis. DESIGN: Retrospective, observational case series. METHODS: We reviewed 26 patients treated for Candida keratitis, including two with recurrent keratitis and one with bilateral infection. RESULTS: Of 29 keratitis episodes resulting from Candida albicans (n = 20) or Candida parapsilosis (n = 9), 16 (55%) complicated chronic ocular surface disease, and nine (31%) followed previous keratoplasty. Only two were clinically suspected to have keratomycosis at initial presentation, and 21 (72%) used antibacterial therapy before corneal scrapings. Reconstructive keratoplasty occurred more often in previously grafted eyes (P = .03). Visual outcome was 20/60 or better in six (100%) medically treated eyes with good presenting visual acuity but in only five eyes (24%) with worse initial vision (P = .002). CONCLUSIONS: Candida keratitis is an opportunistic infection of a compromised cornea that often is misdiagnosed initially and, despite antifungal therapy, occasionally requires corneal grafting.

Clinical characteristics and outcome of Candida keratitis. Publishing Authors By Initials

RL Sun,DB Jones,KR Wilhelmus,

For similar visual acuity research abstracts see: visual acuity research

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Clinical characteristics and outcome of Candida keratitis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: American journal of ophthalmology

VOLUME: 143

Page Numbers: 1043-1045

Journal Abbreviation: Am. J. Ophthalmol.

ISSN: 0002-9394

DAY: 3

MONTH: Jun

YEAR: 2007

Clinical characteristics and outcome of Candida keratitis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370500

Clinical characteristics and outcome of Candida keratitis. Keywords Mesh Terms:

KEYWORDS: Visual Acuity

MESH TERMS: drug therapy

Chemical & Substance for Abstract: Clinical characteristics and outcome of Candida keratitis. Information

Substance Name: Amphotericin B

Registry Number: 1397-89-3

Grant and Affiliation Information for Clinical characteristics and outcome of Candida keratitis.

AFFILIATION: Sid W. Richardson Ocular Microbiology Laboratory, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, USA.

Country: United States

AGENCY: United States NEI

GRANT: EY02520

ACRONYM: EY

MEDLINETA: Am J Ophthalmol

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