Clinical assessment of endothelial dysfunction: combine and rule.

Clinical assessment of endothelial dysfunction: combine and rule. Research Abstract Details 

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Clinical assessment of endothelial dysfunction: combine and rule. Abstract Text:

Michael S Goligorsky,

PURPOSE OF REVIEW: To briefly survey the literature for the past 2-3 years on the subject of diagnostic and prognostic markers of endothelial cell dysfunction. RECENT FINDINGS: Established and emerging techniques to detect endothelial cell dysfunction are divided into two large families: (1) functional and structural markers of endothelial cell dysfunction, and (2) surrogate markers of endothelial cell dysfunction. The first category includes high-resolution Doppler studies of conduit arteries, laser Doppler flowmetry of cutaneous microvasculature, and measurements of arterial stiffness and intima: media thickness. The second category of tests provides brief descriptions of detection of oxidative stress, inflammation, coagulation abnormalities, circulating endothelial cells and microparticles. I also focus on integration of various techniques and some novel genomic, proteomic and metabolomic tests. SUMMARY: This snapshot of existing and emerging technologies diagnosing endothelial cell dysfunction is intended to provide the foundation for the future (a) development of personalized noninvasive screening of endothelial function, and (b) delineation of preclinical diagnostic biomarkers heralding cardiovascular complications.

Clinical assessment of endothelial dysfunction: combine and rule. Publishing Authors By Initials

MS Goligorsky,

For similar diagnosis: laboratory techniques and procedures research abstracts see: diagnosis: laboratory techniques and procedures research

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Clinical assessment of endothelial dysfunction: combine and rule. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in nephrology and hypertension

VOLUME: 15

Page Numbers: 617-24

Journal Abbreviation: Curr. Opin. Nephrol. Hypertens

ISSN: 1062-4821

DAY: 3

MONTH: Nov

YEAR: 2006

Clinical assessment of endothelial dysfunction: combine and rule. Information

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LANGUAGE: eng

NlmUniqueID: 9303753

Clinical assessment of endothelial dysfunction: combine and rule. Keywords Mesh Terms:

KEYWORDS: Laboratory Techniques and Procedures

MESH TERMS: ultrasonography

Chemical & Substance for Abstract: Clinical assessment of endothelial dysfunction: combine and rule. Information

Substance Name: Biological Markers

Registry Number: 0

Grant and Affiliation Information for Clinical assessment of endothelial dysfunction: combine and rule.

AFFILIATION: New York Medical College, Department of Medicine, Valhalla, NY 10595, USA. Michael_Goligorsky@nymc.edu

Country: England

AGENCY: United States NIDDK

GRANT: DK45462

ACRONYM: DK

MEDLINETA: Curr Opin Nephrol Hypertens

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