Clindamycin vs placebo as adjunctive therapy in moderately severe acne.

Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Research Abstract Details 

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Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Abstract Text:

Eighty-three patients with moderately severe acne were entered into a double-blind study utilizing clindamycin and placebo. Counts of comedones and pustules were made at intervals during a 13-week period. Clindamycin resulted in noticeable improvement of acne in 85% of subjects while in the placebo group improvement was present in 38%. There was also an unexplained reduction of total comedone count in the clindamycin-treated group. Severe side effects occurred in two of 44 patients receiving clindamycin (diarrhea, 1 and rash, 1); although an additional eight patients receiving clindamycin experienced mild diarrhea, discontinuation of therapy was not required. Clindamycin appears to be a valuable additional drug in the treatment of acne.

Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Publishing Authors By Initials

For similar pharmaceutical preparations: placebos research abstracts see: pharmaceutical preparations: placebos research

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Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of dermatology

VOLUME: 111

Page Numbers: 997-1000

Journal Abbreviation: Arch Dermatol

ISSN: 0003-987X

DAY: 17

MONTH: Aug

YEAR: 1975

Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Information

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LANGUAGE: eng

NlmUniqueID: 372433

Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Keywords Mesh Terms:

KEYWORDS: Placebos

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: Clindamycin vs placebo as adjunctive therapy in moderately severe acne. Information

Substance Name: Clindamycin

Registry Number: 18323-44-9

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Country: UNITED STATES

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MEDLINETA: Arch Dermatol

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