Classification and immunophenotyping of acute leukemias: a prospective study.

Classification and immunophenotyping of acute leukemias: a prospective study. Research Abstract Details 

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Classification and immunophenotyping of acute leukemias: a prospective study. Abstract Text:

S Pervez,M Khurshid,

Over a period of 3-1/2 years, 86 cases of acute leukemia were analyzed by immunohistochemical (IHC) means on ficoll separated cytospin preparations of peripheral blood and/or bone marrow samples. Antibodies included in the panel were specific against Tdt, HLA-DR, CD19/CD20/CD22, CALLA (CD10), CD2, CD11C as well as against Ig heavy chains. Of 86 cases analyzed, 48 cases were of ALL, (25 of common pre-B ALL, 15 of pre-B/NULL and 8 of T ALL phenotype), twenty-four (24) out of 86 cases were of non-lymphoblastic (AML/AMML) type. In six cases, there was suggestion of a mixed lineage, while in 8 cases there was inconclusive diagnosis. Mean age was lower in common ALL sub-set of ALL as compared to pre-B/NULL group (i.e., 8 vs 12 years), while in non-lymphoblastic group it was 36 years. T cell phenotype was invariably seen in young adults, who usually presented with a mediastinal mass.

Classification and immunophenotyping of acute leukemias: a prospective study. Publishing Authors By Initials

S Pervez,M Khurshid,

For similar investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: cohort studies: longitudinal studies: prospective studies research abstracts see: investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: cohort studies: longitudinal studies: prospective studies research

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Classification and immunophenotyping of acute leukemias: a prospective study. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: JPMA. The Journal of the Pakistan Medical Associat

VOLUME: 47

Page Numbers: 103-6

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ISSN: 0030-9982

DAY: 12

MONTH: Apr

YEAR: 1997

Classification and immunophenotyping of acute leukemias: a prospective study. Information

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LANGUAGE: eng

NlmUniqueID: 7501162

Classification and immunophenotyping of acute leukemias: a prospective study. Keywords Mesh Terms:

KEYWORDS: Prospective Studies

MESH TERMS: pathology

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Grant and Affiliation Information for Classification and immunophenotyping of acute leukemias: a prospective study.

AFFILIATION: Department of Pathology, Aga Khan University Hospital, Karachi.

Country: PAKISTAN

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MEDLINETA: J Pak Med Assoc

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