Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine.

Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Research Abstract Details 

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Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Abstract Text:

The distribution of classical swine fever virus (CSFV) in plasma, monocytes, T and B lymphocytes in peripheral blood was monitored during experimentally induced acute classical swine fever infection in piglets. Six piglets were infected with 10(3.8) TCID50 of virus and blood samples taken up to 18 days post-inoculation (p.i.). Infectious virus was detected in monocytes, T and B lymphocytes to similar titres in five of the six infected piglets. Infectious virus was detected earlier in plasma than in any of the mononuclear cell subpopulations. No significant difference was observed in the period of time in which virus could be isolated from the three cell subpopulations. While a progressive lymphopenia developed, a marked B cell depletion was observed. However, B cells were apparently replaced by non-IgM-bearing mononuclear cells, as the proportion 'total lymphocyte/total leucocytes' remained unaltered throughout the experiment. Virus titres in plasma and peripheral blood mononuclear cells showed a tendency to increase as the disease progressed to its outcome.

Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Publishing Authors By Initials

For similar virus diseases: viremia research abstracts see: virus diseases: viremia research

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Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zentralblatt für Veterinärmedizin. Reihe B. Journa

VOLUME: 46

Page Numbers: 585-93

Journal Abbreviation: Zentralblatt Veterinarmedizin

ISSN: 0514-7166

DAY: 13

MONTH: Nov

YEAR: 1999

Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Information

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LANGUAGE: eng

NlmUniqueID: 331325

Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Keywords Mesh Terms:

KEYWORDS: Viremia

MESH TERMS: virology

Chemical & Substance for Abstract: Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Information

Substance Name: Antibodies, Viral

Registry Number: 0

Grant and Affiliation Information for Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine.

AFFILIATION: Centro de Pesquisas Veterinárias Desidério Finamor, Fundação Estadual de Pesquisa Agropecuária, Eldorado do Sul, RS, Brazil.

Country: GERMANY

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MEDLINETA: Zentralbl Veterinarmed B

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