Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina.

Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina. Research Abstract Details 

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Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina. Abstract Text:

M Namihira,S Honma,H Abe,S Masubuchi,M Ikeda,K Honmaca,

Circadian expression, light-responsiveness and localization of clock genes, rPer1 and rPer2, were examined in the rat retina under constant darkness. A significant circadian variation was detected in rPer2 transcript levels with a peak at ZT14, but not in the rPer1. A light pulse given after constant darkness of 3 days increased both rPer1 and rPer2 expression phase-dependently, while rPer1 was induced at more times than rPer2. A major site of these gene expression within the retina was the inner nuclear layer. These findings indicate that rPer1 and rPer2 genes play different roles in the generation and regulation of circadian rhythms in the retina from those in the suprachiasmatic nucleus.

Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina. Publishing Authors By Initials

M Namihira,S Honma,H Abe,S Masubuchi,M Ikeda,K Honmaca,

For similar proteins: transcription factors research abstracts see: proteins: transcription factors research

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Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Neuroreport

VOLUME: 12

Page Numbers: 471-5

Journal Abbreviation: Neuroreport

ISSN: 0959-4965

DAY: 5

MONTH: Mar

YEAR: 2001

Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina. Information

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LANGUAGE: eng

NlmUniqueID: 9100935

Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina. Keywords Mesh Terms:

KEYWORDS: Transcription Factors

MESH TERMS: genetics

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Substance Name: Transcription Factors

Registry Number: 0

Grant and Affiliation Information for Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina.

AFFILIATION: Department of Physiology, Hokkaido University School of Medicine, Sapporo, Japan.

Country: England

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MEDLINETA: Neuroreport

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