Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide.

Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide. Research Abstract Details 

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Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide. Abstract Text:

E N Sargent,W Boswell,J Hubsher,

The effect of intravenous and intramuscular administration of ceruletide on gallbladder contraction was investigated in 67 normal volunteers and patients. Of the 45 normal volunteers, 33 received the drug intravenously and 12 intramuscularly in graded ascending doses. By either means of injection, ceruletide produced a substantial contraction of the gallbladder with a measurable reduction in gallbladder area. Based on findings in these groups, the 22 patients requiring oral cholecystography for clinical evaluation received 0.3 microgram/kg intramuscularly. The intramuscular administration of synthetic ceruletide after oral cholecystography, in a dose of 0.o microgram/kg, afforded a safe and effective means of gallbladder contraction, with resultant cystic and common bile duct visualization. Side effects occurred less frequently when the drug was administered intramuscularly and were minimal and self-limiting. Peak contraction (40% or greater reduction in size) occurred as early as 5-15 min after after intramuscular injection and in most instances within 30 min.

Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide. Publishing Authors By Initials

EN Sargent,W Boswell,J Hubsher,

For similar persons: age groups: adult: middle aged research abstracts see: persons: age groups: adult: middle aged research

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Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 130

Page Numbers: 1051-5

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Jun

YEAR: 1978

Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide. Keywords Mesh Terms:

KEYWORDS: Middle Aged

MESH TERMS: drug effects

Chemical & Substance for Abstract: Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide. Information

Substance Name: Caerulein

Registry Number: 17650-98-5

Grant and Affiliation Information for Cholecystokinetic cholecystography: efficacy and tolerance studies of ceruletide.

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Country: UNITED STATES

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MEDLINETA: AJR Am J Roentgenol

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