Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals.

Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals. Research Abstract Details 

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Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals. Abstract Text:

Bernard Ng,Rafeef Abugharbieh,Samantha J Palmer,Martin J McKeown,Bernard Ng,Rafeef Abugharbieh,Samantha J Palmer,Martin J McKeown,

We present a new functional magnetic resonance imaging (fMRI) analysis method that incorporates both spatial and temporal dynamics of blood-oxygen-level dependent (BOLD) signals within a region of interest (ROI). 3D moment descriptors are used to characterize the spatial changes in BOLD signals over time. The method is tested on fMRI data collected from eight healthy subjects performing a bulb-squeezing motor task with their right-hand at various frequencies. Multiple brain regions including the left cerebellum, both primary motor cortices (MI), both supplementary motor areas (SMA), left prefrontal cortex (PFC), and left anterior cingulate cortex (ACC) demonstrate significant task-related changes. Furthermore, our method is able to discriminate differences in activation patterns at the various task frequencies, whereas using a traditional intensity based method, no significant activation difference is detected. This suggests that temporal dynamics of the spatial distribution of BOLD signal provide additional information regarding task-related activation thus complementing conventional intensity-based approaches.

Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals. Publishing Authors By Initials

B Ng,R Abugharbieh,SJ Palmer,MJ McKeown,B Ng,R Abugharbieh,SJ Palmer,MJ McKeown,

For similar psychological phenomena and processes: psychology, applied: human engineering: task performance and analysis research abstracts see: psychological phenomena and processes: psychology, applied: human engineering: task performance and analysis research

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Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Medical image computing and computer-assisted inte

VOLUME: 10

Page Numbers: 767-74

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DAY: 3

MONTH: 01

YEAR: 2007

Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals. Information

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LANGUAGE: eng

NlmUniqueID: 101249582

Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals. Keywords Mesh Terms:

KEYWORDS: Task Performance and Analysis

MESH TERMS: methods

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Grant and Affiliation Information for Characterizing task-related temporal dynamics of spatial activation distributions in fMRI BOLD signals.

AFFILIATION: Department of Electrical and Computer Engineering, Pacific Parkinson's Research Center, University of British Columbia, Vancouver, BC, Canada. bernardn@ece.ubc.ca

Country: Germany

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MEDLINETA: Med Image Comput Comput Assist

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