Characterization of gangliosides from equine kidney and spleen.

Characterization of gangliosides from equine kidney and spleen. Research Abstract Details 

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Characterization of gangliosides from equine kidney and spleen. Abstract Text:

S Gasa,A Makita,

Gangliosides were isolated from equine kidney and spleen, and their carbohydrate and lipid moieties were characterized. Among the long-chain bases, considerable proportions of trihydroxy bases (42.3 to 61.2% of the total bases), in which phytosphingosine was predominant were found in all the ganglioside classes. The other major base was sphingosine. Among the constituent fatty acids, long-chain acids (with a carbon number of more than 20), comprised approximately half the total acids, with some alpha-hydroxy and mono-unsaturated acids. By means of sequential hydrolysis with glycosidases coupled with methylation analysis, the following kidney and spleen gangliosides were characterized: hematoside containing both N-acetyl and N-glycolylneuraminic acids; ganglioside GM2 having both types off sialic acid; ganglioside GM1 having mainly N-glycolylneuraminic acid (83 to 86%); ganglioside GD1a having mainly N-glycolylneuraminic acid (71 to 95%). Ganglioside GD3 containing almost exclusively N-glycolylneuraminic acid (93%) was found in the kidney, and ganglioside GD1b having both types of sialic acid in the spleen.

Characterization of gangliosides from equine kidney and spleen. Publishing Authors By Initials

S Gasa,A Makita,

For similar tissues: lymphoid tissue: spleen research abstracts see: tissues: lymphoid tissue: spleen research

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Characterization of gangliosides from equine kidney and spleen. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 88

Page Numbers: 1119-28

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Oct

YEAR: 1980

Characterization of gangliosides from equine kidney and spleen. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Characterization of gangliosides from equine kidney and spleen. Keywords Mesh Terms:

KEYWORDS: Spleen

MESH TERMS: analysis

Chemical & Substance for Abstract: Characterization of gangliosides from equine kidney and spleen. Information

Substance Name: Sphingosine

Registry Number: 123-78-4

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Country: JAPAN

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MEDLINETA: J Biochem

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