Changes of liver and muscle enzymes activity in patients with rigor.

Changes of liver and muscle enzymes activity in patients with rigor. Research Abstract Details 

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Changes of liver and muscle enzymes activity in patients with rigor. Abstract Text:

Nikolaos Sevastos,Emanuel K Manesis,Savvas P Savvas,Nikolaos Galiatsatos,George V Papatheodoridis,Athanasios J Archimandritis,

AIM: We investigated whether changes of liver and muscle enzymes activity are associated with rigor of several causes and have any prognostic significance. METHODS: Seventy-five patients with rigor were prospectively evaluated. Serum enzymes were measured at the onset of rigor and during the three following days. RESULTS: Causes of rigor were bacteremia (n=28), cholangiitis (n=12), protozoan infections (n=9), viral infections (n=10) and platelet transfusions (n=16). Increases in enzymes activity were observed with rigors from infectious causes, but not with that following platelet transfusions. Patients with cholangiitis demonstrated the highest ALT elevations, while those with viral infections the highest CPK levels. In bacteremia, CPK values increased significantly only in cases with dehydration and hypokalemia. CONCLUSIONS: Rigor per se does not cause increases in muscle or liver enzymes activities. Rather these changes are associated with the rigor's causative agent (infectious or not), the patient's general condition and the severity and extent of the underlying disease.

Changes of liver and muscle enzymes activity in patients with rigor. Publishing Authors By Initials

N Sevastos,EK Manesis,SP Savvas,N Galiatsatos,GV Papatheodoridis,AJ Archimandritis,

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Changes of liver and muscle enzymes activity in patients with rigor. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of internal medicine

VOLUME: 19

Page Numbers: 109-14

Journal Abbreviation: Eur. J. Intern. Med.

ISSN: 0953-6205

DAY: 10

MONTH: 01

YEAR: 2008

Changes of liver and muscle enzymes activity in patients with rigor. Information

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LANGUAGE: eng

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AFFILIATION: 2nd Department of Internal Medicine, National University of Athens Medical School, Hippokration General Hospital, 114 Vas. Sophias ave., 11527 Athens, Greece.

Country: Netherlands

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MEDLINETA: Eur J Intern Med

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