Changes in matrix phosphorylation during bovine dentin development.

Changes in matrix phosphorylation during bovine dentin development. Research Abstract Details 

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Changes in matrix phosphorylation during bovine dentin development. Abstract Text:

Kostas Verdelis,Lyudmilla Lukashova,Mitsuo Yamauchi,Peter Atsawasuwan,John T Wright,Margaret G E Peterson,Divya Jha,Adele L Boskey,

Phosphorylation of the organic matrix proteins of dentin is important for the initiation of mineralization, but its relevance in later mineralization stages is controversial. The objective of this study was to analyze changes in the total matrix phosphate content during dentin development and to identify their origin. Amino acid and total matrix phosphate analyses of microdissected developing mantle and circumpulpal fetal bovine dentin specimens were performed. The amino acid composition showed few changes during mantle and circumpulpal dentin maturation. However, the total matrix phosphate content showed a significant, positive correlation with tissue maturation in both mantle and circumpulpal dentin, with a two- and a three-fold increase, respectively, being observed. The data indicate that changes occur in the pattern of phosphorylation of matrix proteins during dentin maturation, which we suggest may play a functional role in later stages of tooth mineralization.

Changes in matrix phosphorylation during bovine dentin development. Publishing Authors By Initials

K Verdelis,L Lukashova,M Yamauchi,P Atsawasuwan,JT Wright,MG Peterson,D Jha,AL Boskey,

For similar reproductive and urinary physiology: reproduction: pregnancy research abstracts see: reproductive and urinary physiology: reproduction: pregnancy research

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Changes in matrix phosphorylation during bovine dentin development. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: European journal of oral sciences

VOLUME: 115

Page Numbers: 296-302

Journal Abbreviation: Eur. J. Oral Sci.

ISSN: 0909-8836

DAY: 3

MONTH: Aug

YEAR: 2007

Changes in matrix phosphorylation during bovine dentin development. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9504563

Changes in matrix phosphorylation during bovine dentin development. Keywords Mesh Terms:

KEYWORDS: Pregnancy

MESH TERMS: metabolism

Chemical & Substance for Abstract: Changes in matrix phosphorylation during bovine dentin development. Information

Substance Name: Phosphoproteins

Registry Number: 0

Grant and Affiliation Information for Changes in matrix phosphorylation during bovine dentin development.

AFFILIATION: The Hospital for Special Surgery, 535 E. 70th Street, New York, NY 10021, USA.

Country: Denmark

AGENCY: United States NIDCR

GRANT: DE 10489

ACRONYM: DE

MEDLINETA: Eur J Oral Sci

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