Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat.

Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat. Research Abstract Details 

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Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat. Abstract Text:

I Urban,D de Wied,

The present experiments tested the sensitivity of theta activity to ACTH 4-10 a peptide known to facilitate the maintenance of conditioned behaviors. Hippocampal theta activity was induced by electrical stimulation of the reticular formation in freely moving rats. The administration of ACTH 4-10 produced a typical 0.5 c/s shift indominant frequency and an increase in 7.5-9.0 c/s components of induced theta activity. The effects were maximal between 60-120 min after subcutaneous injection and lasted several hours. The fact, that a similar effect could be obtained by an increase in stimulus intensity suggests an elevated excitability in the theta generating system in the presence of the peptide. The possible significance of this finding for the maintenance of learned behavior is discussed.

Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat. Publishing Authors By Initials

I Urban,D de Wied,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

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Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Experimental brain research. Experimentelle Hirnfo

VOLUME: 24

Page Numbers: 325-34

Journal Abbreviation:

ISSN: 0014-4819

DAY: 26

MONTH: Jan

YEAR: 1976

Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat. Information

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LANGUAGE: eng

NlmUniqueID: 43312

Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: drug effects

Chemical & Substance for Abstract: Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat. Information

Substance Name: Adrenocorticotropic Hormone

Registry Number: 9002-60-2

Grant and Affiliation Information for Changes in excitability of the theta activity generating substrate by ACTH 4-10 in the rat.

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Country: GERMANY, WEST

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MEDLINETA: Exp Brain Res

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