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Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance.

Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance. Research Abstract Details 

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  • Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance. Abstract Text:

    seong hyun kimSeong Hyun Kim,hyo k limHyo K Lim,dongil choiDongil Choi,won jae leeWon Jae Lee,seung hoon kimSeung Hoon Kim,min ju kimMin Ju Kim,soon jin leeSoon Jin Lee,jae hoon limJae Hoon Lim,

    OBJECTIVE: The purpose of our study was to determine the frequency of bile duct changes after radiofrequency ablation for hepatocellular carcinoma and to evaluate their clinical significance. MATERIALS AND METHODS: Between April 1999 and August 2003, 389 patients with 521 hepatocellular carcinomas underwent a total of 571 sessions of radiofrequency ablation. The maximum dimension of the tumors measured on sonography was 2.4 +/- 0.9 cm (mean +/- SD) (range, 0.5-5.0 cm). The frequency and type of bile duct changes resulting from radiofrequency ablation, the time interval between radiofrequency ablation and the first appearance of bile duct changes, and the serial changes at follow-up CT were analyzed. Complications related to bile duct changes were also evaluated by reviewing medical records and CT scans. RESULTS: Bile duct changes occurred in 69 (12%) of 571 sessions and 66 (17%) of 389 patients. Bile duct changes seen on CT included mild dilatation of upstream bile ducts surrounding the ablation zone in 57 patients (82.6%), biloma in the ablation zone in four patients (5.8%), and both in eight patients (11.6%). The mean time interval between radiofrequency ablation and the initial appearance of bile duct change was 1.6 months (range, immediate-9 months). Most (87%) of the 69 patients with bile duct changes showed no progression on follow-up CT, and only nine (13%) had slight progression. All patients but one, in whom cholangitis developed, had no major complications requiring specific treatment during the follow-up period. CONCLUSION: Although bile duct changes were frequent after the radiofrequency ablation of hepatocellular carcinoma, most were of no clinical significance, and major complications requiring additional treatment were rare.

    Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance. Publishing Authors By Initials

    sh kimSH Kim,hk limHK Lim,d choiD Choi,wj leeWJ Lee,sh kimSH Kim,mj kimMJ Kim,sj leeSJ Lee,jh limJH Lim,

    For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, interventional research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, interventional research

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    Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: AJR. American journal of roentgenology

    VOLUME: 183

    Page Numbers: 1611-7

    Journal Abbreviation:

    ISSN: 0361-803X

    DAY: 15

    MONTH: Dec

    YEAR: 2004

    Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7708173

    Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance. Keywords Mesh Terms:

    KEYWORDS: Ultrasonography, Interventional

    MESH TERMS: surgery

    Chemical & Substance for Abstract: Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance. Information

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    Grant and Affiliation Information for Changes in bile ducts after radiofrequency ablation of hepatocellular carcinoma: frequency and clinical significance.

    AFFILIATION: Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, Ilwon-dong, Kangnam-ku, Seoul 135-710, South Korea.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: AJR Am J Roentgenol

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