Changed pharmacokinetics under the influence of age.

Changed pharmacokinetics under the influence of age. Research Abstract Details 

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Changed pharmacokinetics under the influence of age. Abstract Text:

Age significantly affects therapeutics in both general and specific ways. In newborns and in infants various physiological processes are still developing, whereas in elderly there may be decreased efficiency or capacity of physiological processes. Unexpected or 'idiosyncratic' responses to drugs in the very old or in the very young often can be explained by age-related changes in absorption, distribution, metabolism, end-organ responsiveness and excretion. Adolescence is often associated with rapid growth and changing body composition. Special problems with adolescents are poor compliance and drug abuse. Adults show a rather stable pharmacokinetic profile, although the cardiac output diminishes and the peripheral resistance increases about 1% annually. Exposure to enzyme-inducing agents (nicotine, cimetidine) influences the pharmacokinetic parameters of both adolescents and adults.

Changed pharmacokinetics under the influence of age. Publishing Authors By Initials

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Changed pharmacokinetics under the influence of age. Journal Published:

PUBLICATION TYPE: Review

Journal: Pharmaceutisch weekblad. Scientific edition

VOLUME: 9

Page Numbers: 50-5

Journal Abbreviation:

ISSN: 0167-6555

DAY: 24

MONTH: Apr

YEAR: 1987

Changed pharmacokinetics under the influence of age. Information

Number of References: 22

LANGUAGE: eng

NlmUniqueID: 7907992

Changed pharmacokinetics under the influence of age. Keywords Mesh Terms:

KEYWORDS: Pharmaceutical Preparations

MESH TERMS: urine

Chemical & Substance for Abstract: Changed pharmacokinetics under the influence of age. Information

Substance Name: Pharmaceutical Preparations

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Grant and Affiliation Information for Changed pharmacokinetics under the influence of age.

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Country: NETHERLANDS

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MEDLINETA: Pharm Weekbl Sci

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