Cetuximab in non-small cell lung cancer.

Cetuximab in non-small cell lung cancer. Research Abstract Details 

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Cetuximab in non-small cell lung cancer. Abstract Text:

Foluso O Ademuyiwa,Nasser Hanna,Foluso O Ademuyiwa,Nasser Hanna,Foluso O Ademuyiwa,Nasser Hanna,

Advanced non-small cell lung carcinoma (NSCLC) remains a challenge to treat due to its high local and systemic recurrence. The overall survival remains poor despite the approval of several new chemotherapeutic agents in the management of advanced NSCLC. Overexpression or mutations in the EGFR have been shown to be associated with a significant percentage of NSCLC. The development of targeted agents, such as cetuximab, against the EGFR is therefore a rational objective. Several preclinical and clinical studies suggest that cetuximab is active against NSCLC. This paper reviews the application of cetuximab in NSCLC.

Cetuximab in non-small cell lung cancer. Publishing Authors By Initials

FO Ademuyiwa,N Hanna,FO Ademuyiwa,N Hanna,FO Ademuyiwa,N Hanna,

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Cetuximab in non-small cell lung cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Expert opinion on biological therapy

VOLUME: 8

Page Numbers: 107-13

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ISSN: 1744-7682

DAY: 17

MONTH: Jan

YEAR: 2008

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LANGUAGE: eng

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AFFILIATION: Indiana University School of Medicine, Division of Hematology/Oncology, 535 Barnhill Drive, RT 473, Indianapolis, IN 46202, USA +1 317 278 6942 ; +1 317 278 4910 ; fademuyi@iupui.edu.

Country: England

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MEDLINETA: Expert Opin Biol Ther

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