Cerebellar ataxia in a patient receiving calcineurin inhibitors after living donor liver transplantation: a case report.

Cerebellar ataxia in a patient receiving calcineurin inhibitors after living donor liver transplantation: a case report. Research Abstract Details 

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Cerebellar ataxia in a patient receiving calcineurin inhibitors after living donor liver transplantation: a case report. Abstract Text:

I Yamaguchi,T Ichikawa,K Nakao,K Hamasaki,K Hirano,S Eguchi,M Takatsuki,Y Kawasita,T Kanematsu,K Eguchi,I Yamaguchi,T Ichikawa,K Nakao,K Hamasaki,K Hirano,S Eguchi,M Takatsuki,Y Kawasita,T Kanematsu,K Eguchi,I Yamaguchi,T Ichikawa,K Nakao,K Hamasaki,K Hirano,S Eguchi,M Takatsuki,Y Kawasita,T Kanematsu,K Eguchi,

Neurological complications of calcineurin inhibitors are frequent problems after transplantation. Cerebellar ataxia with other neurological findings and an abnormal density area in the subcortical white matter are found by MRI in the brains of most patients with central nervous system complications caused by calcineurin inhibitors. Such neurological complications are not life-threatening, but have a negative impact on the quality of life. We describe a 58-year-old woman who developed cerebellar ataxia at 4 days after living donor liver transplantation. She walked with a swaying gait, and after walking for 5 minutes she was unable to stand. Her symptoms persisted after a change from tacrolimus to cyclosporine, but dose reduction of cyclosporine and addition of mycophenolate mofetil cured the ataxia. We diagnosed a case of cerebellar ataxia without leukoencephalopathy or other neurological symptoms, as a new complication of calcineurin inhibitor treatment. We concluded that careful attention should be paid to neurological complications of calcineurin inhibitors.

Cerebellar ataxia in a patient receiving calcineurin inhibitors after living donor liver transplantation: a case report. Publishing Authors By Initials

I Yamaguchi,T Ichikawa,K Nakao,K Hamasaki,K Hirano,S Eguchi,M Takatsuki,Y Kawasita,T Kanematsu,K Eguchi,I Yamaguchi,T Ichikawa,K Nakao,K Hamasaki,K Hirano,S Eguchi,M Takatsuki,Y Kawasita,T Kanematsu,K Eguchi,I Yamaguchi,T Ichikawa,K Nakao,K Hamasaki,K Hirano,S Eguchi,M Takatsuki,Y Kawasita,T Kanematsu,K Eguchi,

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Cerebellar ataxia in a patient receiving calcineurin inhibitors after living donor liver transplantation: a case report. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Transplantation proceedings

VOLUME: 39

Page Numbers: 3495-7

Journal Abbreviation: Transplant. Proc.

ISSN: 0041-1345

DAY: 19

MONTH: Dec

YEAR: 2007

Cerebellar ataxia in a patient receiving calcineurin inhibitors after living donor liver transplantation: a case report. Information

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LANGUAGE: eng

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AFFILIATION: First Department of Internal Medicine, Graduate School of Biomedical Science, Nagasaki University, Nagasaki, Japan.

Country: United States

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MEDLINETA: Transplant Proc

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