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Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells.

Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells. Research Abstract Details 

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  • Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells. Abstract Text:

    j s mitchenerJ S Mitchener,j d shelburneJ D Shelburne,w d bradfordW D Bradford,h k hawkinsH K Hawkins,

    Morphologic alterations in HeLa cells deprived of serum and amino acids were studied by light and electron microscopy. After complete deprivation for 1, 3, or 6 hours, many cells contained autophagic vacuoles enclosing clearly recognizable cell organelles. The proportion of cells showing autophagy rose from 4 to 37% in the first 3 hours of deprivation. Acid phosphatase reaction product was localized within many of the autophagic vacuoles by a modified Gomori method. After 12 to 24 hours of deprivation, many membranous residual bodies were noted within the starved HeLa cells. These electron microscopic studies indicate that complete deprivation of serum and amino acids provides a useful model for the further study of cellular autophagocytosis.

    Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells. Publishing Authors By Initials

    js mitchenerJS Mitchener,jd shelburneJD Shelburne,wd bradfordWD Bradford,hk hawkinsHK Hawkins,

    For similar biological phenomena, cell phenomena, and immunity: cell physiology: endocytosis: phagocytosis research abstracts see: biological phenomena, cell phenomena, and immunity: cell physiology: endocytosis: phagocytosis research

    PUBMED ID PMID:

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    Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: The American journal of pathology

    VOLUME: 83

    Page Numbers: 485-92

    Journal Abbreviation: Am. J. Pathol.

    ISSN: 0002-9440

    DAY: 20

    MONTH: Jun

    YEAR: 1976

    Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 370502

    Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells. Keywords Mesh Terms:

    KEYWORDS: Phagocytosis

    MESH TERMS: ultrastructure

    Chemical & Substance for Abstract: Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells. Information

    Substance Name: Amino Acids

    Registry Number: 0

    Grant and Affiliation Information for Cellular autophagocytosis induced by deprivation of serum and amino acids in HeLa cells.

    AFFILIATION:

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Am J Pathol

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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