CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen.

CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen. Abstract Text:

The CD5+B lymphocyte (B1a) population is known to be involved in most immune responses to microorganism TI antigens. Moreover, xid mice deficient for immune responses against TI-2 antigens are known to lack the B1a population, suggesting a role for B1a cells in TI-2 immune responses. We previously established that the oligosaccharide human blood group A antigen stimulated murine TI-2 immune responses. In this work, we show that the frequency of anti-A-secreting hybridomas was higher in mice with larger splenic B1a populations and that in vivo anti-CD5 treatment reduced anti-A immune response without affecting the response against TD RBC antigens. A similar effect was observed by in vitro anti-CD5 treatment of splenocytes. The in vivo anti-CD5 treatment also interfered with the immunization-dependent increase in splenocyte numbers. These results are in agreement with an important role for the B-cell CD5 receptor in the regulation of TI-2 immune responses possibly mediated by its interaction with the CD72 ligand.

CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen. Publishing Authors By Initials

For similar cells: cells, cultured: tumor cells, cultured research abstracts see: cells: cells, cultured: tumor cells, cultured research

PUBMED ID PMID:

MEDLINE DATE: 1997 Aug-Dec

CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Immunological investigations

VOLUME: 26

Page Numbers: 631-47

Journal Abbreviation: Immunol. Invest.

ISSN: 0882-0139

DAY: 6

MONTH: 05

YEAR: 2008

CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8504629

CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen. Keywords Mesh Terms:

KEYWORDS: Tumor Cells, Cultured

MESH TERMS: immunology

Chemical & Substance for Abstract: CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen. Information

Substance Name: CD72 protein, human

Registry Number: 0

Grant and Affiliation Information for CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen.

AFFILIATION: Canadian Red Cross Society, Blood Services, Québec City center, Sainte-Foy, Canada.

Country: UNITED STATES

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Immunol Invest

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen Related Publications

• A nutritional intervention promoting a mediterranean food pattern does not affect total daily dietary cost in north american women in free-living conditions.
• BOLD and perfusion changes during epileptic generalised spike wave activity.
• CD5+ B cell-dependent regulation of the murine T-cell independent immune response against the human blood group A antigen.
• Changes in the population pattern as revealed by the 1951 census.
• Coronary thrombolysis: adjuvant revascularization surgery.
• Defined weight expectations in overweight women: anthropometrical, psychological and eating behavioral correlates.
• Effect of a nutritional intervention promoting the Mediterranean food pattern on anthropometric profile in healthy women from the Québec city metropolitan area.
• Fully automatic segmentation of the hippocampus and the amygdala from MRI using hybrid prior knowledge.
• Immunomodulatory and anti-inflammatory potential of a malleable protein matrix composed of concentrated fermented whey proteins.
• Independent component analysis of interictal fMRI in focal epilepsy: comparison with general linear model-based EEG-correlated fMRI.
• Isolation and characterization of eceriferum (cer) mutants induced by T-DNA insertions in Arabidopsis thaliana.
• Molecular recognition in chiral smectic liquid crystals: The effect of core-core interactions and chirality transfer on polar order.
• Myotonic dystrophy type I in childhood Long-term evolution in patients surviving the neonatal period.
• Not Available
• Personality traits in overweight and obese women: Associations with BMI and eating behaviors.
• Photoinduced polarization inversion in a ferroelectric liquid crystal using an ambidextrous chiral thioindigo dopant.
• Postcoronary thrombolysis management.
• Psychiatry and rehabilitation.
• Synthesis of the t [beta-D-Gal-(1 goes to 3)-alpha-D-GalNAc]-antigenic determinant in a form useful for the preparation of an effective artificial antigen and the corresponding immunoadsorbent.
• Temporal lobe interictal epileptic discharges affect cerebral activity in "default mode" brain regions.
• The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles.
• The WHO and NCEP/ATPIII Definitions of the Metabolic Syndrome in Postmenopausal Women: Are They So Different?
• The murine NK2.1 antigen: a 130 kD glycoprotein dimer expressed by a natural killer cell subset of the spleen, thymus and lymph nodes.
• Transmission of influenza A in human beings - Authors' reply.
• [" Erasme " shelter.]
• [Elaboration and application of a program of public dental health]
• [Encephalopathy of hepatic origin. I. Clinical syndrome & pathogenic conception.]
• [Group experience : risks and stakes.]
• [Not Available.]
• [Prevention and chronicity in community psychiatry.]