Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications.

Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Research Abstract Details 

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Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Abstract Text:

Fong Ying Yeoh,Roxanne R Cuasito,Christina C Capule,Freeman M Wong,Weiming Wu,

The pKa's of the 6-CH groups of 1,3-dimethyluracil, N-methyl-2-pyridone, and N-methyl-4-pyridone were determined through their reactions with bases derived from carbon acids with known pKa and the reactions of their corresponding carbanions with the carbon acids. No correlation between the stability of the carbanions and the rate of decarboxylation of corresponding carboxylic acids was found.

Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Publishing Authors By Initials

FY Yeoh,RR Cuasito,CC Capule,FM Wong,W Wu,

For similar heterocyclic compounds: heterocyclic compounds, 1-ring: pyridines: pyridones research abstracts see: heterocyclic compounds: heterocyclic compounds, 1-ring: pyridines: pyridones research

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Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Bioorganic chemistry

VOLUME: 35

Page Numbers: 338-43

Journal Abbreviation: Bioorg. Chem.

ISSN: 0045-2068

DAY: 2

MONTH: 04

YEAR: 2007

Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 1303703

Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Keywords Mesh Terms:

KEYWORDS: Pyridones

MESH TERMS: chemistry

Chemical & Substance for Abstract: Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications. Information

Substance Name: Orotic Acid

Registry Number: 65-86-1

Grant and Affiliation Information for Carbanions from decarboxylation of orotate analogs: stability and mechanistic implications.

AFFILIATION: Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: 5 S06 GM52588

ACRONYM: GM

MEDLINETA: Bioorg Chem

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