Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera.

Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera. Research Abstract Details 

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Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera. Abstract Text:

Hugh M Robertson,Karl H J Gordon,

The draft assembly of the honey bee Apis mellifera genome sequence reveals that the 17 centromeric-distal telomeres are of a simple, shared, and canonical structure, with 3-4 kb of a unique subtelomeric sequence, followed by several kilobases of TTAGG or variant telomeric repeats. This simple subtelomeric structure differs from the centromeric-proximal telomeres on the short arms of the 15 acrocentric chromosomes, which are apparently composed primarily of the 176-bp AluI tandem repeat. This dichotomy between the distal and proximal telomeres may involve differential participation of the telomeres of the 15 acrocentric chromosomes in the Rabl configuration after mitosis and the chromosome bouquet in meiotic prophase I. As expected from the presence of canonical TTAGG telomeric repeats, we identified a candidate telomerase gene in the bee, as well as the silkmoth Bombyx mori and the flour beetle Tribolium castaneum.

Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera. Publishing Authors By Initials

HM Robertson,KH Gordon,

For similar animals: invertebrates: arthropods: insects: beetles: tribolium research abstracts see: animals: invertebrates: arthropods: insects: beetles: tribolium research

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Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Genome research

VOLUME: 16

Page Numbers: 1345-51

Journal Abbreviation: Genome Res.

ISSN: 1088-9051

DAY: 25

MONTH: 10

YEAR: 2006

Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9518021

Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera. Keywords Mesh Terms:

KEYWORDS: Tribolium

MESH TERMS: genetics

Chemical & Substance for Abstract: Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera. Information

Substance Name: Telomerase

Registry Number: EC 2.7.7.49

Grant and Affiliation Information for Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera.

AFFILIATION: Department of Entomology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. hughrobe@uiuc.edu

Country: United States

AGENCY: United States NIAID

GRANT: AI56081

ACRONYM: AI

MEDLINETA: Genome Res

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