Cancers of the respiratory tract in mustard gas workers.

Cancers of the respiratory tract in mustard gas workers. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Cancers of the respiratory tract in mustard gas workers. Abstract Text:

In a study of a cohort of 2498 men and 1032 women employed in the manufacture of mustard gas in Cheshire during the second world war 3354 (95%) individuals were successfully traced for mortality to the end of 1984. Large and highly significant excesses were observed as compared with national death rates for deaths from cancer of the larynx (11 deaths observed, 4.04 expected, p = 0.003), pharynx (15 observed, 2.73 expected, p less than 0.001), and all other buccal cavity and upper respiratory sites combined (lip, tongue, salivary gland, mouth, nose) (12 observed, 4.29 expected, p = 0.002). For lung cancer, a highly significant but more moderate excess was observed (200 observed, 138.39 expected, p less than 0.001). Significant excesses were also observed for deaths from acute and chronic non-malignant respiratory disease (131 observed, 91.87 expected and 185 observed, 116.31 expected, respectively). The risks for cancers of the pharynx and lung were significantly related to duration of employment. None of these results is substantially altered when expected numbers are calculated from Cheshire urban areas rather than national rates, although the relative risks for lung cancer and non-malignant respiratory disease are substantially reduced if rates for Merseyside, the nearest large conurbation, are used. The results provide strong evidence that exposure to mustard gas can cause cancers of the upper respiratory tract and some evidence that it can cause lung cancer and non-malignant respiratory disease.(ABSTRACT TRUNCATED AT 250 WORDS)

Cancers of the respiratory tract in mustard gas workers. Publishing Authors By Initials

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

PUBMED ID PMID:

MEDLINE DATE:

Cancers of the respiratory tract in mustard gas workers. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: British journal of industrial medicine

VOLUME: 45

Page Numbers: 652-9

Journal Abbreviation: Br J Ind Med

ISSN: 0007-1072

DAY: 28

MONTH: Oct

YEAR: 1988

Cancers of the respiratory tract in mustard gas workers. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370637

Cancers of the respiratory tract in mustard gas workers. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: mortality

Chemical & Substance for Abstract: Cancers of the respiratory tract in mustard gas workers. Information

Substance Name: Mustard Gas

Registry Number: 505-60-2

Grant and Affiliation Information for Cancers of the respiratory tract in mustard gas workers.

AFFILIATION: Section of Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK.

Country: ENGLAND

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Br J Ind Med

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Cancers of the respiratory tract in mustard gas workers Related Publications

• A CROSS-NATIONAL STUDY OF BUENOS AIRES AND CHICAGO ADOLESCENTS.
• A study of the chromosome damage persisting after x-ray therapy for ankylosing spondylitis.
• AGE AT ONSET OF LUNG CANCER: SIGNIFICANCE IN RELATION TO EFFECT OF SMOKING.
• Are we winning the war against cancer? A review in memory of Keith Durrant.
• Ballistic arterial trauma to the lower extremity: recent South African experience.
• Cancer of the lung and nose in nickel workers.
• Cancers of the respiratory tract in mustard gas workers.
• Childhood leukaemia in greater London: a search for evidence of clustering.
• DECOMPRESSION SICKNESS AMONG U.S. NAVY OPERATIONAL DIVERS: AN ESTIMATE OF INCIDENCE USING AIR DECOMPRESSION TABLES. RES REP 4-64.
• Epidemiological evidence of the effects of behaviour and the environment on the risk of human cancer.
• Exposure to vinyl chloride and angiosarcoma of the liver: a report of the register of cases.
• Inhibition of cyclin-dependent kinases - a review of the recent patent literature.
• Interpretation of chromosome counts made on bone-marrow cells.
• Investigation of relation between use of oral contraceptives and thromboembolic disease.
• Major epidemics of the 20th century: from coronary thrombosis to AIDS.
• Mortality from cancer and other causes after radiotherapy for ankylosing spondylitis.
• Mortality from lung cancer in asbestos workers 1955.
• Mortality from lung cancer in asbestos workers.
• Mortality of nitrate fertiliser workers.
• Oral contraceptives and thromboembolic disease.
• Organic impairment simulating mental deficiency.
• PEER RATING VALIDITY AS A FUNCTION OF RATER INTELLIGENCE AND RATING SCORE RECEIVED. PROJ MR005.13-5001, SUBTASK 1, REP 24.
• The smoking-induced epidemic.
• The treatment of septicemia of newborn foals with streptomycin and penicillin.
• Tumours in a tropical country. Foreword.
• Was the study big enough? Two "café" rules (Editorial).
• [Bacteriological investigations on albothyl used in leukorrhea therapy.]
• [Not Available.]
• [Not Available.]
• [Used motor oil poisoning in cattle. Report of a clinical case]