Can immunization affect the development of allergy?

Can immunization affect the development of allergy? Research Abstract Details 

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Can immunization affect the development of allergy? Abstract Text:

A changing pattern of infections may be of importance for the increase in prevalence of asthma and other allergic diseases in developed countries during recent decades. The clear inverse relation between number of siblings and atopy observed in several studies may be related to a protective role of infections, although specific information is inconclusive. A recent study showed that positive tuberculin responses in schoolchildren correlated with a lower prevalence of atopic disorders, but other studies did not find a relation between BCG vaccination and allergic disease or sensitization. Transient production of IgE antibodies to pertussis toxin has been demonstrated after pertussis immunization; however, randomized clinical trials involving both whole cell and acellular pertussis vaccines have failed to show any enhancement of atopic manifestations in children. Epidemiologic investigations indicate that viral infections may either promote (RSV) or inhibit (hepatitis A, measles) atopy, although data are scarce. In conclusion, the evidence is limited regarding a direct role of vaccinations for development of atopic manifestations, but speaks against a major effect of some types of vaccinations. On the other hand, since some infections may offer protection in relation to allergy, vaccination could result in an increased risk.

Can immunization affect the development of allergy? Publishing Authors By Initials

For similar virus diseases research abstracts see: virus diseases research

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Can immunization affect the development of allergy? Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pediatric allergy and immunology : official public

VOLUME: 11 Suppl 13

Page Numbers: 26-8

Journal Abbreviation: Pediatr Allergy Immunol

ISSN: 0905-6157

DAY: 28

MONTH: 05

YEAR: 2000

Can immunization affect the development of allergy? Information

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LANGUAGE: eng

NlmUniqueID: 9106718

Can immunization affect the development of allergy? Keywords Mesh Terms:

KEYWORDS: Virus Diseases

MESH TERMS: immunology

Chemical & Substance for Abstract: Can immunization affect the development of allergy? Information

Substance Name: Viral Vaccines

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Grant and Affiliation Information for Can immunization affect the development of allergy?

AFFILIATION: Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Country: DENMARK

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MEDLINETA: Pediatr Allergy Immunol

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