Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside.

Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside. Research Abstract Details 

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Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside. Abstract Text:

M A Borger,R D Weisel,

Calcium channel blockers constitute a very important group of drugs that are commonly used in the treatment of cardiovascular and cerebrovascular disorders. Current indications for these medications include hypertension, angina, supraventricular arrhythmias, and prevention of coronary and cerebral vasospasm. Although calcium channel blockers originally held great promise in the treatment of myocardial and cerebral ischemia, clinical results have been discouraging. An understanding of the basic physiological mechanisms of actions for these drugs is important for the practising clinician and may explain the disappointing results for the treatment of ischemia to date. This paper is a narrative review, from a clinician's viewpoint, of the structure and role of calcium channels in cardiac and cerebrovascular tissues, as well as a review of the in vitro and clinical results of calcium channel blockade in myocardial and cerebral ischemia.

Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside. Publishing Authors By Initials

MA Borger,RD Weisel,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside. Journal Published:

PUBLICATION TYPE: Review

Journal: The Canadian journal of cardiology

VOLUME: 15

Page Numbers: 333-40

Journal Abbreviation:

ISSN: 1916-7075

DAY: 3

MONTH: Mar

YEAR: 1999

Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside. Information

Number of References: 59

LANGUAGE: eng

NlmUniqueID: 8510280

Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: metabolism

Chemical & Substance for Abstract: Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside. Information

Substance Name: Calcium Channels

Registry Number: 0

Grant and Affiliation Information for Calcium channel blockers in myocardial and cerebral ischemia: a clinician's review from bench to bedside.

AFFILIATION: Division of Cardiovascular Surgery and Cardiovascular Sciences Collaborative Program, University of Toronto, Toronto, Canada.

Country: CANADA

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MEDLINETA: Can J Cardiol

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