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Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer.

Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer. Research Abstract Details 

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  • Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer. Abstract Text:

    t rottT Rott,b luzarB Luzar,j sorliJ Sorli,

    The survivors of laryngeal cancer have an increased risk of second primary cancer, especially in the lung. Therefore, the authors were interested, if there is an increase of precancerous lesions or malignancies in bronchopulmonary biopsies of the patients after laryngeal cancer treatment. There were 70 (38 transbronchial and 32 bronchial) of 5,097 bronchopulmonary biopsies in 58 patients (55 men and 3 women) with history of laryngeal carcinoma. The age of the patients ranged from 39 to 81 years (mean value 62.5 years). The biopsies were performed from 1 month to 23 years after surgical treatment and/or radiation therapy due to squamous laryngeal carcinoma. The frequency of metaplastic, dysplastic and tumorous lesions was contrary to expectation a bit lower than in routine bronchial biopsies. But in contrast with the latter, metastases were 10 times more common among tumorous lesions. In 19 of 58 patients malignancies appeared from 1 month up to 276 months after laryngectomy. Four patients had definitively, and another 5 very probably second primary carcinoma. Ten patients presented with metastases from laryngeal cancer. The possibilities to differentiate metastatic laryngeal and second primary carcinoma are discussed.

    Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer. Publishing Authors By Initials

    t rottT Rott,b luzarB Luzar,j sorliJ Sorli,

    For similar neoplasms: neoplasms, second primary research abstracts see: neoplasms: neoplasms, second primary research

    PUBMED ID PMID:

    MEDLINE DATE:

    Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Acta oto-laryngologica. Supplementum

    VOLUME: 527

    Page Numbers: 167-9

    Journal Abbreviation:

    ISSN: 0365-5237

    DAY: 13

    MONTH: 02

    YEAR: 1997

    Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 370355

    Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer. Keywords Mesh Terms:

    KEYWORDS: Neoplasms, Second Primary

    MESH TERMS: diagnosis

    Chemical & Substance for Abstract: Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer. Information

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    Grant and Affiliation Information for Bronchopulmonary changes after laryngeal cancer treatment--differentiation between metastatic laryngeal and second primary cancer.

    AFFILIATION: Institute of Pathology, Medical Faculty, Ljubljana, Slovenia. rott@ibmi.mf.uni-lj.si

    Country: NORWAY

    NORWAY Research PublicationNORWAY Research Publication

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    MEDLINETA: Acta Otolaryngol Suppl

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