Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan.

Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan. Research Abstract Details 

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Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan. Abstract Text:

M S Siddiqui,N Kayani,M S Gill,S Pervez,S Muzaffar,S A Aziz,Z Setna,M Israr,S H Hasan,

OBJECTIVE: To know the frequency of breast diseases in Pakistani females. METHODS: A retrospective analysis of 3279 breast specimens received over a period of 4 years (1993-1996) at the department of pathology, the Aga Khan University Hospital. RESULTS: Out of a total of 3279 breast specimens, common breast lesions included infiltrating duct carcinoma 37%, followed by fibro adenoma 16.95%, fibrocystic change 13.96%, mastitis 6.83% and duct ectasia 5.33%. Majority of the cases of infiltrating duct carcinoma were encountered in the 5th and 6th decades of life. Tumour size was 2 or >2 cms. in 93% of cases and 40% of them showed 3 or >3 positive lymph nodes. Grade I tumours were 11.38%, grade II 59.17% and grade III tumours 29.47%. Correlation of grade with lymph node metastases (3 or >3+ve nodes) showed 15 cases (1.53%) of grade I, 178 cases (18.25%) of grade II and 68 (6.97%) cases of grade III tumours. CONCLUSION: This study shows that in Pakistani females, the most commonly encountered lesion in carcinoma of the breast followed by the benign lesions such as fibro adenoma, fibrocystic disease & others. Breast carcinoma occurs at a younger age group with predominance of high-grade lesions and with frequent lymph node metastasis.

Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan. Publishing Authors By Initials

MS Siddiqui,N Kayani,MS Gill,S Pervez,S Muzaffar,SA Aziz,Z Setna,M Israr,SH Hasan,

For similar investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research abstracts see: investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research

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Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: JPMA. The Journal of the Pakistan Medical Associat

VOLUME: 53

Page Numbers: 94-7

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ISSN: 0030-9982

DAY: 12

MONTH: Mar

YEAR: 2003

Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan. Information

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LANGUAGE: eng

NlmUniqueID: 7501162

Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan. Keywords Mesh Terms:

KEYWORDS: Retrospective Studies

MESH TERMS: epidemiology

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Grant and Affiliation Information for Breast diseases: a histopathological analysis of 3279 cases at a tertiary care center in Pakistan.

AFFILIATION: Department of Pathology, Aga Khan University Hospital, Karachi.

Country: Pakistan

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MEDLINETA: J Pak Med Assoc

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