Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication.

Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication. Abstract Text:

Benoît Mesurolle,Michèle Ariche,David Cohen,

OBJECTIVE: The purpose of this study was to review the nature of adverse reactions, or "breakthrough reactions," experienced by patients who received steroid premedication and low-osmolar contrast media. We compared the demographics of patients having these breakthrough reactions with those of patients who did not develop these reactions. MATERIALS AND METHODS: We retrospectively reviewed our radiology quality improvement database to identify patients with breakthrough reactions that occurred from January 1, 1994, through October 1, 1999, and we reviewed their medical records. We compared these patients with a control cohort of patients who had a history of prior adverse reaction to contrast media but no breakthrough reaction after administration of low-osmolar contrast media and premedication with corticosteroids. RESULTS: Over the 6-year period, 52 patients experienced 61 breakthrough reactions. The breakthrough reaction was mild in 76% of the patients. The breakthrough reaction was similar to the patient's initial adverse reaction in 85% of the patients. A history of seafood allergy or hay fever was statistically more likely to be identified in the breakthrough group than the control group. CONCLUSION: Breakthrough reactions occur in a substantial number of patients despite premedication with steroids and use of low-osmolar contrast agents. Typically the breakthrough reaction is of similar severity to the patient's initial reaction. Severe or life-threatening reactions are seen in 24% of patients.

Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication. Publishing Authors By Initials

B Mesurolle,M Ariche,D Cohen,

For similar investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research

PUBMED ID PMID:

MEDLINE DATE:

Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 176

Page Numbers: 1389-92

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Jun

YEAR: 2001

Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708173

Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication. Keywords Mesh Terms:

KEYWORDS: Risk Factors

MESH TERMS: epidemiology

Chemical & Substance for Abstract: Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication. Information

Substance Name: Contrast Media

Registry Number: 0

Grant and Affiliation Information for Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication.

AFFILIATION: Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: AJR Am J Roentgenol

REFSOURCE: AJR Am J Roentgenol. 2002 Mar;178(3):766

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication Related Publications

• Breakthrough adverse reactions to low-osmolar contrast media after steroid premedication.
• Endocrine Regulation of the Fasting Response by PPARalpha-Mediated Induction of Fibroblast Growth Factor 21.
• High-level aureomycin dosage in anaplasmosis.
• Identification of a hormonal basis for gallbladder filling.
• Innominate artery occlusive disease: sonographic findings.
• Liver receptor homolog-1 regulates bile Acid homeostasis but is not essential for feedback regulation of bile Acid synthesis.
• Nutrition and ischemic stroke.
• Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.
• Rôle of the Doctor of Medicine in the Life and Health of the American Citizen.
• Sonographic evaluation of spleen size in tall healthy athletes.
• Sonography of benign cystic teratoma of the ovary: pitfalls in diagnosis.
• The role of depression and dissociation in the relationship between childhood trauma and bulimic symptoms among ethnically diverse female undergraduates.
• The spectrum of abdominal venous CT findings in blunt trauma.
• Violence exposure and cortisol responses in urban youth.
• Writing it up: a step-by-step guide to publication for beginning investigators.