Brain cancer diagnosis and therapy with nanoplatforms.

Brain cancer diagnosis and therapy with nanoplatforms. Research Abstract Details 

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Brain cancer diagnosis and therapy with nanoplatforms. Abstract Text:

Yong-Eun Lee Koo,G Ramachandra Reddy,Mahaveer Bhojani,Randy Schneider,Martin A Philbert,Alnawaz Rehemtulla,Brian D Ross,Raoul Kopelman,

Treatment of brain cancer remains a challenge despite recent improvements in surgery and multimodal adjuvant therapy. Drug therapies of brain cancer have been particularly inefficient, due to the blood-brain barrier and the non-specificity of the potentially toxic drugs. The nanoparticle has emerged as a potential vector for brain delivery, able to overcome the problems of current strategies. Moreover, multi-functionality can be engineered into a single nanoplatform so that it can provide tumor-specific detection, treatment, and follow-up monitoring. Such multitasking is not possible with conventional technologies. This review describes recent advances in nanoparticle-based detection and therapy of brain cancer. The advantages of nanoparticle-based delivery and the types of nanoparticle systems under investigation are described, as well as their applications.

Brain cancer diagnosis and therapy with nanoplatforms. Publishing Authors By Initials

YE Koo,GR Reddy,M Bhojani,R Schneider,MA Philbert,A Rehemtulla,BD Ross,R Kopelman,

For similar therapeutics: combined modality therapy: photochemotherapy research abstracts see: therapeutics: combined modality therapy: photochemotherapy research

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Brain cancer diagnosis and therapy with nanoplatforms. Journal Published:

PUBLICATION TYPE: Review

Journal: Advanced drug delivery reviews

VOLUME: 58

Page Numbers: 1556-77

Journal Abbreviation: Adv. Drug Deliv. Rev.

ISSN: 0169-409X

DAY: 28

MONTH: 09

YEAR: 2006

Brain cancer diagnosis and therapy with nanoplatforms. Information

Number of References: 127

LANGUAGE: eng

NlmUniqueID: 8710523

Brain cancer diagnosis and therapy with nanoplatforms. Keywords Mesh Terms:

KEYWORDS: Photochemotherapy

MESH TERMS: trends

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Grant and Affiliation Information for Brain cancer diagnosis and therapy with nanoplatforms.

AFFILIATION: Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

Country: Netherlands

AGENCY: United States NCI

GRANT: R24CA83099

ACRONYM: CA

MEDLINETA: Adv Drug Deliv Rev

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